Alessi DR - Search Results

1

Deficiency of LKB1 in heart prevents ischemia-mediated activation of AMPKalpha2 but not AMPKalpha1.

Sakamoto K, Zarrinpashneh E, Budas GR, Pouleur AC, Dutta A, Prescott AR, Vanoverschelde JL, Ashworth A, Jovanović A, Alessi DR, Bertrand L. Sakamoto K, et al. Among authors: alessi dr. Am J Physiol Endocrinol Metab. 2006 May;290(5):E780-8. doi: 10.1152/ajpendo.00443.2005. Epub 2005 Dec 6. Am J Physiol Endocrinol Metab. 2006. PMID: 16332922 Free PMC article.

2

Identification of the sites in MAP kinase kinase-1 phosphorylated by p74raf-1.

Alessi DR, Saito Y, Campbell DG, Cohen P, Sithanandam G, Rapp U, Ashworth A, Marshall CJ, Cowley S. Alessi DR, et al. EMBO J. 1994 Apr 1;13(7):1610-9. doi: 10.1002/j.1460-2075.1994.tb06424.x. EMBO J. 1994. PMID: 8157000 Free PMC article.

3

Assay and expression of mitogen-activated protein kinase, MAP kinase kinase, and Raf.

Alessi DR, Cohen P, Ashworth A, Cowley S, Leevers SJ, Marshall CJ. Alessi DR, et al. Methods Enzymol. 1995;255:279-90. doi: 10.1016/s0076-6879(95)55031-3. Methods Enzymol. 1995. PMID: 8524112 No abstract available.

4

3-Phosphoinositide-dependent protein kinase-1 (PDK1): structural and functional homology with the Drosophila DSTPK61 kinase.

Alessi DR, Deak M, Casamayor A, Caudwell FB, Morrice N, Norman DG, Gaffney P, Reese CB, MacDougall CN, Harbison D, Ashworth A, Bownes M. Alessi DR, et al. Curr Biol. 1997 Oct 1;7(10):776-89. doi: 10.1016/s0960-9822(06)00336-8. Curr Biol. 1997. PMID: 9368760 Free article.

5

Mechanism of activation and function of protein kinase B.

Alessi DR, Cohen P. Alessi DR, et al. Curr Opin Genet Dev. 1998 Feb;8(1):55-62. doi: 10.1016/s0959-437x(98)80062-2. Curr Opin Genet Dev. 1998. PMID: 9529606 Review.

6

Heart 6-phosphofructo-2-kinase activation by insulin results from Ser-466 and Ser-483 phosphorylation and requires 3-phosphoinositide-dependent kinase-1, but not protein kinase B.

Bertrand L, Alessi DR, Deprez J, Deak M, Viaene E, Rider MH, Hue L. Bertrand L, et al. Among authors: alessi dr. J Biol Chem. 1999 Oct 22;274(43):30927-33. doi: 10.1074/jbc.274.43.30927. J Biol Chem. 1999. PMID: 10521487 Free article.

7

Partial purification and characterization of a wortmannin-sensitive and insulin-stimulated protein kinase that activates heart 6-phosphofructo-2-kinase.

Deprez J, Bertrand L, Alessi DR, Krause U, Hue L, Rider MH. Deprez J, et al. Among authors: alessi dr. Biochem J. 2000 Apr 1;347 Pt 1(Pt 1):305-12. Biochem J. 2000. PMID: 10727432 Free PMC article.

8

Essential role of PDK1 in regulating cell size and development in mice.

Lawlor MA, Mora A, Ashby PR, Williams MR, Murray-Tait V, Malone L, Prescott AR, Lucocq JM, Alessi DR. Lawlor MA, et al. Among authors: alessi dr. EMBO J. 2002 Jul 15;21(14):3728-38. doi: 10.1093/emboj/cdf387. EMBO J. 2002. PMID: 12110585 Free PMC article.

9

Ionizing radiation induces ataxia telangiectasia mutated kinase (ATM)-mediated phosphorylation of LKB1/STK11 at Thr-366.

Sapkota GP, Deak M, Kieloch A, Morrice N, Goodarzi AA, Smythe C, Shiloh Y, Lees-Miller SP, Alessi DR. Sapkota GP, et al. Among authors: alessi dr. Biochem J. 2002 Dec 1;368(Pt 2):507-16. doi: 10.1042/BJ20021284. Biochem J. 2002. PMID: 12234250 Free PMC article.

10

Deficiency of PDK1 in cardiac muscle results in heart failure and increased sensitivity to hypoxia.

Mora A, Davies AM, Bertrand L, Sharif I, Budas GR, Jovanović S, Mouton V, Kahn CR, Lucocq JM, Gray GA, Jovanović A, Alessi DR. Mora A, et al. Among authors: alessi dr. EMBO J. 2003 Sep 15;22(18):4666-76. doi: 10.1093/emboj/cdg469. EMBO J. 2003. PMID: 12970179 Free PMC article.

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