Axonal damage is T cell mediated and occurs concomitantly with demyelination in mice infected with a neurotropic coronavirus.
Dandekar AA, Wu GF, Pewe L, Perlman S.
Dandekar AA, et al. Among authors: perlman s.
J Virol. 2001 Jul;75(13):6115-20. doi: 10.1128/JVI.75.13.6115-6120.2001.
J Virol. 2001.
PMID: 11390613
Free PMC article.
Immunodeficient MHV-infected RAG1-/- mice (mice defective in recombinase activating gene 1 expression) do not develop demyelination unless they receive splenocytes from a mouse previously immunized against MHV (G. F. Wu, A. Dandekar, L. Pewe, and S. Perlman, J. Immu …
Immunodeficient MHV-infected RAG1-/- mice (mice defective in recombinase activating gene 1 expression) do not develop demyelination unless t …