Smithgall TE - Search Results

1

An examination of dynamics crosstalk between SH2 and SH3 domains by hydrogen/deuterium exchange and mass spectrometry.

Hochrein JM, Lerner EC, Schiavone AP, Smithgall TE, Engen JR. Hochrein JM, et al. Among authors: smithgall te. Protein Sci. 2006 Jan;15(1):65-73. doi: 10.1110/ps.051782206. Epub 2005 Dec 1. Protein Sci. 2006. PMID: 16322569 Free PMC article.

2

Conformational features of the full-length HIV and SIV Nef proteins determined by mass spectrometry.

Hochrein JM, Wales TE, Lerner EC, Schiavone AP, Smithgall TE, Engen JR. Hochrein JM, et al. Among authors: smithgall te. Biochemistry. 2006 Jun 27;45(25):7733-9. doi: 10.1021/bi060438x. Biochemistry. 2006. PMID: 16784224

3

The Abl SH2-kinase linker naturally adopts a conformation competent for SH3 domain binding.

Chen S, Brier S, Smithgall TE, Engen JR. Chen S, et al. Among authors: smithgall te. Protein Sci. 2007 Apr;16(4):572-81. doi: 10.1110/ps.062631007. Epub 2007 Feb 27. Protein Sci. 2007. PMID: 17327393 Free PMC article.

4

Dynamics of the Tec-family tyrosine kinase SH3 domains.

Roberts JM, Tarafdar S, Joseph RE, Andreotti AH, Smithgall TE, Engen JR, Wales TE. Roberts JM, et al. Among authors: smithgall te. Protein Sci. 2016 Apr;25(4):852-64. doi: 10.1002/pro.2887. Epub 2016 Mar 18. Protein Sci. 2016. PMID: 26808198 Free PMC article.

5

Comparison of SH3 and SH2 domain dynamics when expressed alone or in an SH(3+2) construct: the role of protein dynamics in functional regulation.

Engen JR, Smithgall TE, Gmeiner WH, Smith DL. Engen JR, et al. Among authors: smithgall te. J Mol Biol. 1999 Apr 2;287(3):645-56. doi: 10.1006/jmbi.1999.2619. J Mol Biol. 1999. PMID: 10092465

6

Hydrogen exchange shows peptide binding stabilizes motions in Hck SH2.

Engen JR, Gmeiner WH, Smithgall TE, Smith DL. Engen JR, et al. Among authors: smithgall te. Biochemistry. 1999 Jul 13;38(28):8926-35. doi: 10.1021/bi982611y. Biochemistry. 1999. PMID: 10413466

7

SH3-dependent stimulation of Src-family kinase autophosphorylation without tail release from the SH2 domain in vivo.

Lerner EC, Smithgall TE. Lerner EC, et al. Among authors: smithgall te. Nat Struct Biol. 2002 May;9(5):365-9. doi: 10.1038/nsb782. Nat Struct Biol. 2002. PMID: 11976726

8

Activation of STAT3 by the Src family kinase Hck requires a functional SH3 domain.

Schreiner SJ, Schiavone AP, Smithgall TE. Schreiner SJ, et al. Among authors: smithgall te. J Biol Chem. 2002 Nov 22;277(47):45680-7. doi: 10.1074/jbc.M204255200. Epub 2002 Sep 19. J Biol Chem. 2002. PMID: 12244095 Free article.

9

Activation of the Src family kinase Hck without SH3-linker release.

Lerner EC, Trible RP, Schiavone AP, Hochrein JM, Engen JR, Smithgall TE. Lerner EC, et al. Among authors: smithgall te. J Biol Chem. 2005 Dec 9;280(49):40832-7. doi: 10.1074/jbc.M508782200. Epub 2005 Oct 6. J Biol Chem. 2005. PMID: 16210316 Free article.

10

Src family kinases phosphorylate the Bcr-Abl SH3-SH2 region and modulate Bcr-Abl transforming activity.

Meyn MA 3rd, Wilson MB, Abdi FA, Fahey N, Schiavone AP, Wu J, Hochrein JM, Engen JR, Smithgall TE. Meyn MA 3rd, et al. Among authors: smithgall te. J Biol Chem. 2006 Oct 13;281(41):30907-16. doi: 10.1074/jbc.M605902200. Epub 2006 Aug 15. J Biol Chem. 2006. PMID: 16912036 Free article.

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