Zhou W - Search Results

1

CYP51 from Trypanosoma cruzi: a phyla-specific residue in the B' helix defines substrate preferences of sterol 14alpha-demethylase.

Lepesheva GI, Zaitseva NG, Nes WD, Zhou W, Arase M, Liu J, Hill GC, Waterman MR. Lepesheva GI, et al. Among authors: zhou w. J Biol Chem. 2006 Feb 10;281(6):3577-85. doi: 10.1074/jbc.M510317200. Epub 2005 Nov 30. J Biol Chem. 2006. PMID: 16321980 Free article.

2

CYP51 from Trypanosoma brucei is obtusifoliol-specific.

Lepesheva GI, Nes WD, Zhou W, Hill GC, Waterman MR. Lepesheva GI, et al. Among authors: zhou w. Biochemistry. 2004 Aug 24;43(33):10789-99. doi: 10.1021/bi048967t. Biochemistry. 2004. PMID: 15311940

3

Mechanistic analysis of a multiple product sterol methyltransferase implicated in ergosterol biosynthesis in Trypanosoma brucei.

Zhou W, Lepesheva GI, Waterman MR, Nes WD. Zhou W, et al. J Biol Chem. 2006 Mar 10;281(10):6290-6. doi: 10.1074/jbc.M511749200. Epub 2006 Jan 12. J Biol Chem. 2006. PMID: 16414960 Free article.

4

Biosynthesis of phytosterols. Kinetic mechanism for the enzymatic C-methylation of sterols.

Nes WD, Song Z, Dennis AL, Zhou W, Nam J, Miller MB. Nes WD, et al. Among authors: zhou w. J Biol Chem. 2003 Sep 5;278(36):34505-16. doi: 10.1074/jbc.M303359200. Epub 2003 Jun 13. J Biol Chem. 2003. PMID: 12807886 Free article.

5

Sterol methyltransferase2: purification, properties, and inhibition.

Zhou W, Nes WD. Zhou W, et al. Arch Biochem Biophys. 2003 Dec 1;420(1):18-34. doi: 10.1016/j.abb.2003.08.029. Arch Biochem Biophys. 2003. PMID: 14622971

6

Disruption of ergosterol biosynthesis, growth, and the morphological transition in Candida albicans by sterol methyltransferase inhibitors containing sulfur at C-25 in the sterol side chain.

Kanagasabai R, Zhou W, Liu J, Nguyen TT, Veeramachaneni P, Nes WD. Kanagasabai R, et al. Among authors: zhou w. Lipids. 2004 Aug;39(8):737-46. doi: 10.1007/s11745-004-1290-7. Lipids. 2004. PMID: 15638241

7

Mechanism-based active site modification of the soybean sterol methyltransferase by 26,27-dehydrocycloartenol.

Song Z, Zhou W, Liu J, Nes WD. Song Z, et al. Among authors: zhou w. Bioorg Med Chem Lett. 2004 Jan 5;14(1):33-6. doi: 10.1016/j.bmcl.2003.10.015. Bioorg Med Chem Lett. 2004. PMID: 14684292

8

Substrate-based inhibitors of the (S)-adenosyl-L-methionine:delta24(25)- to delta24(28)-sterol methyl transferase from Saccharomyces cerevisiae.

Nes WD, Guo D, Zhou W. Nes WD, et al. Among authors: zhou w. Arch Biochem Biophys. 1997 Jun 1;342(1):68-81. doi: 10.1006/abbi.1997.9984. Arch Biochem Biophys. 1997. PMID: 9185615

9

Sterol methyltransferase a target for anti-amoeba therapy: towards transition state analog and suicide substrate drug design.

Kidane ME, Vanderloop BH, Zhou W, Thomas CD, Ramos E, Singha U, Chaudhuri M, Nes WD. Kidane ME, et al. Among authors: zhou w. J Lipid Res. 2017 Dec;58(12):2310-2323. doi: 10.1194/jlr.M079418. Epub 2017 Oct 17. J Lipid Res. 2017. PMID: 29042405 Free PMC article.

10

Probing the sterol binding site of soybean sterol methyltransferase by site-directed mutagenesis: functional analysis of conserved aromatic amino acids in Region 1.

Nes WD, Sinha A, Jayasimha P, Zhou W, Song Z, Dennis AL. Nes WD, et al. Among authors: zhou w. Arch Biochem Biophys. 2006 Apr 15;448(1-2):23-30. doi: 10.1016/j.abb.2005.08.022. Epub 2005 Oct 7. Arch Biochem Biophys. 2006. PMID: 16271698

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