Balimane P - Search Results

1

Development of an on-line extraction turbulent flow chromatography tandem mass spectrometry method for cassette analysis of Caco-2 cell based bi-directional assay samples.

Smalley J, Kadiyala P, Xin B, Balimane P, Olah T. Smalley J, et al. Among authors: balimane p. J Chromatogr B Analyt Technol Biomed Life Sci. 2006 Jan 18;830(2):270-7. doi: 10.1016/j.jchromb.2005.11.006. Epub 2005 Nov 22. J Chromatogr B Analyt Technol Biomed Life Sci. 2006. PMID: 16307910

2

Development of a quantitative LC-MS/MS analytical method coupled with turbulent flow chromatography for digoxin for the in vitro P-gp inhibition assay.

Smalley J, Marino AM, Xin B, Olah T, Balimane PV. Smalley J, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2007 Jul 1;854(1-2):260-7. doi: 10.1016/j.jchromb.2007.04.030. Epub 2007 May 1. J Chromatogr B Analyt Technol Biomed Life Sci. 2007. PMID: 17524973

3

Small molecule antagonist of leukocyte function associated antigen-1 (LFA-1): structure-activity relationships leading to the identification of 6-((5S,9R)-9-(4-cyanophenyl)-3-(3,5-dichlorophenyl)-1-methyl-2,4-dioxo-1,3,7-triazaspiro[4.4]nonan-7-yl)nicotinic acid (BMS-688521).

Watterson SH, Xiao Z, Dodd DS, Tortolani DR, Vaccaro W, Potin D, Launay M, Stetsko DK, Skala S, Davis PM, Lee D, Yang X, McIntyre KW, Balimane P, Patel K, Yang Z, Marathe P, Kadiyala P, Tebben AJ, Sheriff S, Chang CY, Ziemba T, Zhang H, Chen BC, DelMonte AJ, Aranibar N, McKinnon M, Barrish JC, Suchard SJ, Murali Dhar TG. Watterson SH, et al. Among authors: balimane p. J Med Chem. 2010 May 13;53(9):3814-30. doi: 10.1021/jm100348u. J Med Chem. 2010. PMID: 20405922

4

A novel high-throughput automated chip-based nanoelectrospray tandem mass spectrometric method for PAMPA sample analysis.

Balimane PV, Pace E, Chong S, Zhu M, Jemal M, Pelt CK. Balimane PV, et al. J Pharm Biomed Anal. 2005 Sep 1;39(1-2):8-16. doi: 10.1016/j.jpba.2005.03.043. J Pharm Biomed Anal. 2005. PMID: 15978768

5

Development of an in silico model for predicting efflux substrates in Caco-2 cells.

Zhang L, Balimane PV, Johnson SR, Chong S. Zhang L, et al. Int J Pharm. 2007 Oct 1;343(1-2):98-105. doi: 10.1016/j.ijpharm.2007.05.017. Epub 2007 May 18. Int J Pharm. 2007. PMID: 17583455

6

Utility of 96 well Caco-2 cell system for increased throughput of P-gp screening in drug discovery.

Balimane PV, Patel K, Marino A, Chong S. Balimane PV, et al. Eur J Pharm Biopharm. 2004 Jul;58(1):99-105. doi: 10.1016/j.ejpb.2004.02.014. Eur J Pharm Biopharm. 2004. PMID: 15207543

7

Cell culture-based models for intestinal permeability: a critique.

Balimane PV, Chong S. Balimane PV, et al. Drug Discov Today. 2005 Mar 1;10(5):335-43. doi: 10.1016/S1359-6446(04)03354-9. Drug Discov Today. 2005. PMID: 15749282 Review.

8

Validation of the 96 well Caco-2 cell culture model for high throughput permeability assessment of discovery compounds.

Marino AM, Yarde M, Patel H, Chong S, Balimane PV. Marino AM, et al. Int J Pharm. 2005 Jun 13;297(1-2):235-41. doi: 10.1016/j.ijpharm.2005.03.008. Epub 2005 Apr 11. Int J Pharm. 2005. PMID: 15907606

9

A combined cell based approach to identify P-glycoprotein substrates and inhibitors in a single assay.

Balimane PV, Chong S. Balimane PV, et al. Int J Pharm. 2005 Sep 14;301(1-2):80-8. doi: 10.1016/j.ijpharm.2005.05.034. Int J Pharm. 2005. PMID: 16023314

10

P-gp inhibition potential in cell-based models: which "calculation" method is the most accurate?

Balimane PV, Marino A, Chong S. Balimane PV, et al. AAPS J. 2008 Dec;10(4):577-86. doi: 10.1208/s12248-008-9068-x. Epub 2008 Dec 11. AAPS J. 2008. PMID: 19082742 Free PMC article.

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