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Page 1
The discovery of fluoropyridine-based inhibitors of the factor VIIa/TF complex--Part 2.
Kohrt JT, Filipski KJ, Cody WL, Cai C, Dudley DA, Van Huis CA, Willardsen JA, Narasimhan LS, Zhang E, Rapundalo ST, Saiya-Cork K, Leadley RJ, Edmunds JJ. Kohrt JT, et al. Among authors: edmunds jj. Bioorg Med Chem Lett. 2006 Feb 15;16(4):1060-4. doi: 10.1016/j.bmcl.2005.10.076. Epub 2005 Nov 11. Bioorg Med Chem Lett. 2006. PMID: 16289811
Nonpeptide angiotensin II receptor antagonists. 2. Design, synthesis, and structure-activity relationships of 2-alkyl-4-(1H-pyrrol-1-yl)-1H-imidazole derivatives: profile of 2-propyl-1-[[2'-(1H-tetrazol-5-yl)-[1,1' -biphenyl]-4-yl]-methyl]-4-[2-(trifluoroacetyl)-1H-pyrrol-1-yl]-1H- imidazole-5-carboxylic acid (CI-996).
Sircar I, Hodges JC, Quin J 3rd, Bunker AM, Winters RT, Edmunds JJ, Kostlan CR, Connolly C, Kesten SJ, Hamby JM, et al. Sircar I, et al. Among authors: edmunds jj. J Med Chem. 1993 Aug 6;36(16):2253-65. doi: 10.1021/jm00068a002. J Med Chem. 1993. PMID: 8360871
Potent bicyclic lactam inhibitors of thrombin: Part I: P3 modifications.
St-Denis Y, Augelli-Szafran CE, Bachand B, Berryman KA, DiMaio J, Doherty AM, Edmunds JJ, Leblond L, Lévesque S, Narasimhan LS, Penvose-Yi JR, Rubin JR, Tarazi M, Winocour PD, Siddiqui MA. St-Denis Y, et al. Among authors: edmunds jj. Bioorg Med Chem Lett. 1998 Nov 17;8(22):3193-8. doi: 10.1016/s0960-894x(98)00550-2. Bioorg Med Chem Lett. 1998. PMID: 9873701
Potent and selective bicyclic lactam inhibitors of thrombin: Part 2: P1 modifications.
Plummer JS, Berryman KA, Cai C, Cody WL, DiMaio J, Doherty AM, Edmunds JJ, He JX, Holland DR, Levesque S, Kent DR, Narasimhan LS, Rubin JR, Rapundalo ST, Siddiqui MA, Susser AJ, St-Denis Y, Winocour PD. Plummer JS, et al. Among authors: edmunds jj. Bioorg Med Chem Lett. 1998 Dec 1;8(23):3409-14. doi: 10.1016/s0960-894x(98)00613-1. Bioorg Med Chem Lett. 1998. PMID: 9873743
Potent and selective bicyclic lactam inhibitors of thrombin: Part 3: P1' modifications.
Plummer JS, Berryman KA, Cai C, Cody WL, DiMaio J, Doherty AM, Eaton S, Edmunds JJ, Holland DR, Lafleur D, Levesque S, Narasimhan LS, Rubin JR, Rapundalo ST, Siddiqui MA, Susser A, St-Denis Y, Winocour P. Plummer JS, et al. Among authors: edmunds jj. Bioorg Med Chem Lett. 1999 Mar 22;9(6):835-40. doi: 10.1016/s0960-894x(99)00096-7. Bioorg Med Chem Lett. 1999. PMID: 10206546
The design of potent and selective inhibitors of thrombin utilizing a piperazinedione template: part 2.
Cody WL, Augelli-Szafran CE, Berryman KA, Cai C, Doherty AM, Edmunds JJ, He JX, Narasimhan LS, Penvose-Yi J, Plummer JS, Rapundalo ST, Rubin JR, Van Huis CA, Leblond L, Winocour PD, Siddiqui MA. Cody WL, et al. Among authors: edmunds jj. Bioorg Med Chem Lett. 1999 Sep 6;9(17):2503-8. doi: 10.1016/s0960-894x(99)00419-9. Bioorg Med Chem Lett. 1999. PMID: 10498197
43 results