Costantino G - Search Results

1

Unveiling hidden features of orphan nuclear receptors: the case of the small heterodimer partner (SHP).

Macchiarulo A, Rizzo G, Costantino G, Fiorucci S, Pellicciari R. Macchiarulo A, et al. Among authors: costantino g. J Mol Graph Model. 2006 Mar;24(5):362-72. doi: 10.1016/j.jmgm.2005.09.016. Epub 2005 Nov 9. J Mol Graph Model. 2006. PMID: 16288980

2

Binding mode of 6ECDCA, a potent bile acid agonist of the farnesoid X receptor (FXR).

Costantino G, Macchiarulo A, Entrena-Guadix A, Camaioni E, Pellicciari R. Costantino G, et al. Bioorg Med Chem Lett. 2003 Jun 2;13(11):1865-8. doi: 10.1016/s0960-894x(03)00281-6. Bioorg Med Chem Lett. 2003. PMID: 12749886

3

Is antagonism of E/Z-guggulsterone at the farnesoid X receptor mediated by a noncanonical binding site? A molecular modeling study.

Meyer U, Costantino G, Macchiarulo A, Pellicciari R. Meyer U, et al. Among authors: costantino g. J Med Chem. 2005 Nov 3;48(22):6948-55. doi: 10.1021/jm0505056. J Med Chem. 2005. PMID: 16250653

4

Metabotropic glutamate receptors: targets for therapy of cerebral ischaemia.

Costantino G, Macchiarulo A, Pellicciari R. Costantino G, et al. Expert Opin Ther Targets. 2001 Dec;5(6):669-683. doi: 10.1517/14728222.5.6.669. Expert Opin Ther Targets. 2001. PMID: 12540277

5

The role of electrostatic interaction in the molecular recognition of selective agonists to metabotropic glutamate receptors.

Macchiarulo A, Costantino G, Sbaglia R, Aiello S, Meniconi M, Pellicciari R. Macchiarulo A, et al. Among authors: costantino g. Proteins. 2003 Mar 1;50(4):609-19. doi: 10.1002/prot.10301. Proteins. 2003. PMID: 12577267

6

Binding modes of noncompetitive AMPA antagonists: a computational approach.

De Luca L, Macchiarulo A, Costantino G, Barreca ML, Gitto R, Chimirri A, Pellicciari R. De Luca L, et al. Among authors: costantino g. Farmaco. 2003 Feb;58(2):107-13. doi: 10.1016/s0014-827x(02)00027-7. Farmaco. 2003. PMID: 12581776

7

Molecular dynamics simulation of the ligand binding domain of mGluR1 in response to agonist and antagonist binding.

Costantino G, Macchiarulo A, Belenikin M, Pellicciari R. Costantino G, et al. J Comput Aided Mol Des. 2002 Nov;16(11):779-84. doi: 10.1023/a:1023876410800. J Comput Aided Mol Des. 2002. PMID: 12825789

8

QSAR study of anticonvulsant negative allosteric modulators of the AMPA receptor.

Macchiarulo A, De Luca L, Costantino G, Barreca ML, Gitto R, Pellicciari R, Chimirri A. Macchiarulo A, et al. Among authors: costantino g. J Med Chem. 2004 Mar 25;47(7):1860-3. doi: 10.1021/jm0310838. J Med Chem. 2004. PMID: 15027880

9

Bile acid derivatives as ligands of the farnesoid X receptor. Synthesis, evaluation, and structure-activity relationship of a series of body and side chain modified analogues of chenodeoxycholic acid.

Pellicciari R, Costantino G, Camaioni E, Sadeghpour BM, Entrena A, Willson TM, Fiorucci S, Clerici C, Gioiello A. Pellicciari R, et al. Among authors: costantino g. J Med Chem. 2004 Aug 26;47(18):4559-69. doi: 10.1021/jm049904b. J Med Chem. 2004. PMID: 15317466

10

Insights into phenylalanine derivatives recognition of VLA-4 integrin: from a pharmacophoric study to 3D-QSAR and molecular docking analyses.

Macchiarulo A, Costantino G, Meniconi M, Pleban K, Ecker G, Bellocchi D, Pellicciari R. Macchiarulo A, et al. Among authors: costantino g. J Chem Inf Comput Sci. 2004 Sep-Oct;44(5):1829-39. doi: 10.1021/ci049914l. J Chem Inf Comput Sci. 2004. PMID: 15446843

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