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Specific targeting highly conserved residues in the HIV-1 reverse transcriptase primer grip region. Design, synthesis, and biological evaluation of novel, potent, and broad spectrum NNRTIs with antiviral activity.
Fattorusso C, Gemma S, Butini S, Huleatt P, Catalanotti B, Persico M, De Angelis M, Fiorini I, Nacci V, Ramunno A, Rodriquez M, Greco G, Novellino E, Bergamini A, Marini S, Coletta M, Maga G, Spadari S, Campiani G. Fattorusso C, et al. Among authors: coletta m. J Med Chem. 2005 Nov 17;48(23):7153-65. doi: 10.1021/jm050257d. J Med Chem. 2005. PMID: 16279773
Development of Potent Inhibitors of the Mycobacterium tuberculosis Virulence Factor Zmp1 and Evaluation of Their Effect on Mycobacterial Survival inside Macrophages.
Paolino M, Brindisi M, Vallone A, Butini S, Campiani G, Nannicini C, Giuliani G, Anzini M, Lamponi S, Giorgi G, Sbardella D, Ferraris DM, Marini S, Coletta M, Palucci I, Minerva M, Delogu G, Pepponi I, Goletti D, Cappelli A, Gemma S, Brogi S. Paolino M, et al. Among authors: coletta m. ChemMedChem. 2018 Mar 6;13(5):422-430. doi: 10.1002/cmdc.201700759. Epub 2018 Feb 14. ChemMedChem. 2018. PMID: 29334428
Electrostatic Map Of Proteasome α-Rings Encodes The Design of Allosteric Porphyrin-Based Inhibitors Able To Affect 20S Conformation By Cooperative Binding.
Dato AD, Cunsolo A, Persico M, Santoro AM, D'Urso A, Milardi D, Purrello R, Stefanelli M, Paolesse R, Tundo GR, Sbardella D, Fattorusso C, Coletta M. Dato AD, et al. Among authors: coletta m. Sci Rep. 2017 Dec 6;7(1):17098. doi: 10.1038/s41598-017-17008-7. Sci Rep. 2017. PMID: 29213119 Free PMC article.
Cooperative Binding of the Cationic Porphyrin Tris-T4 Enhances Catalytic Activity of 20S Proteasome Unveiling a Complex Distribution of Functional States.
Santoro AM, D'Urso A, Cunsolo A, Milardi D, Purrello R, Sbardella D, Tundo GR, Diana D, Fattorusso R, Dato AD, Paladino A, Persico M, Coletta M, Fattorusso C. Santoro AM, et al. Among authors: coletta m. Int J Mol Sci. 2020 Sep 29;21(19):7190. doi: 10.3390/ijms21197190. Int J Mol Sci. 2020. PMID: 33003385 Free PMC article.
Modulation of the catalytic activity of neutrophil collagenase MMP-8 on bovine collagen I. Role of the activation cleavage and of the hemopexin-like domain.
Gioia M, Fasciglione GF, Marini S, D'Alessio S, De Sanctis G, Diekmann O, Pieper M, Politi V, Tschesche H, Coletta M. Gioia M, et al. Among authors: coletta m. J Biol Chem. 2002 Jun 28;277(26):23123-30. doi: 10.1074/jbc.M110873200. Epub 2002 Apr 12. J Biol Chem. 2002. PMID: 11953425 Free article.
F., De Sanctis, G., D'Alessio, S., Politi, V., and Coletta, M. (2000) J. Biol. Chem. 275, 18657-18663), whereas the catalytic domain lacks this specificity and cleaves the collagen molecule at multiple sites. ...Thus, the PheMMP-8 species is characterized by a much …
F., De Sanctis, G., D'Alessio, S., Politi, V., and Coletta, M. (2000) J. Biol. Chem. 275, 18657-18663), whereas the catalytic …
Cooperativity and allostery in haemoglobin function.
Ciaccio C, Coletta A, De Sanctis G, Marini S, Coletta M. Ciaccio C, et al. Among authors: coletta a, coletta m. IUBMB Life. 2008 Feb;60(2):112-23. doi: 10.1002/iub.6. IUBMB Life. 2008. PMID: 18380000 Free article. Review.
466 results