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Page 1
Novel non-benzimidazole chk2 kinase inhibitors.
McClure KJ, Huang L, Arienti KL, Axe FU, Brunmark A, Blevitt J, Breitenbucher JG. McClure KJ, et al. Among authors: breitenbucher jg. Bioorg Med Chem Lett. 2006 Apr 1;16(7):1924-8. doi: 10.1016/j.bmcl.2005.12.096. Epub 2006 Jan 25. Bioorg Med Chem Lett. 2006. PMID: 16442290
SAR studies of 1,5-diarylpyrazole-based CCK1 receptor antagonists.
Gomez L, Hack MD, McClure K, Sehon C, Huang L, Morton M, Li L, Barrett TD, Shankley N, Breitenbucher JG. Gomez L, et al. Among authors: breitenbucher jg. Bioorg Med Chem Lett. 2007 Dec 1;17(23):6493-8. doi: 10.1016/j.bmcl.2007.09.093. Epub 2007 Oct 1. Bioorg Med Chem Lett. 2007. PMID: 17933530
3-[5-(3,4-Dichloro-phenyl)-1-(4-methoxy-phenyl)-1H-pyrazol-3-yl]-2-m-tolyl-propionate (JNJ-17156516), a novel, potent, and selective cholecystokinin 1 receptor antagonist: in vitro and in vivo pharmacological comparison with dexloxiglumide.
Morton MF, Barrett TD, Yan W, Freedman JM, Lagaud G, Prendergast CE, Moreno V, Pyati J, Figueroa K, Li L, Wu X, Rizzolio M, Breitenbucher JG, McClure K, Shankley NP. Morton MF, et al. Among authors: breitenbucher jg. J Pharmacol Exp Ther. 2007 Nov;323(2):562-9. doi: 10.1124/jpet.107.124578. Epub 2007 Aug 7. J Pharmacol Exp Ther. 2007. PMID: 17684117
Identification of 2-arylbenzimidazoles as potent human histamine H4 receptor ligands.
Lee-Dutra A, Arienti KL, Buzard DJ, Hack MD, Khatuya H, Desai PJ, Nguyen S, Thurmond RL, Karlsson L, Edwards JP, Breitenbucher JG. Lee-Dutra A, et al. Among authors: breitenbucher jg. Bioorg Med Chem Lett. 2006 Dec 1;16(23):6043-8. doi: 10.1016/j.bmcl.2006.08.117. Epub 2006 Sep 20. Bioorg Med Chem Lett. 2006. PMID: 16990005
Discovery and synthesis of 6,7,8,9-tetrahydro-5H-pyrimido-[4,5-d]azepines as novel TRPV1 antagonists.
Hawryluk NA, Merit JE, Lebsack AD, Branstetter BJ, Hack MD, Swanson N, Ao H, Maher MP, Bhattacharya A, Wang Q, Freedman JM, Scott BP, Wickenden AD, Chaplan SR, Breitenbucher JG. Hawryluk NA, et al. Among authors: breitenbucher jg. Bioorg Med Chem Lett. 2010 Dec 1;20(23):7137-41. doi: 10.1016/j.bmcl.2010.09.023. Epub 2010 Sep 17. Bioorg Med Chem Lett. 2010. PMID: 20947352
46 results