Ward SA - Search Results

1

Enantiomeric 1,2,4-trioxanes display equivalent in vitro antimalarial activity versus Plasmodium falciparum malaria parasites: implications for the molecular mechanism of action of the artemisinins.

O'Neill PM, Rawe SL, Borstnik K, Miller A, Ward SA, Bray PG, Davies J, Oh CH, Posner GH. O'Neill PM, et al. Among authors: ward sa. Chembiochem. 2005 Nov;6(11):2048-54. doi: 10.1002/cbic.200500048. Chembiochem. 2005. PMID: 16222725

2

Rapid chloroquine efflux phenotype in both chloroquine-sensitive and chloroquine-resistant Plasmodium falciparum. A correlation of chloroquine sensitivity with energy-dependent drug accumulation.

Bray PG, Howells RE, Ritchie GY, Ward SA. Bray PG, et al. Among authors: ward sa. Biochem Pharmacol. 1992 Oct 6;44(7):1317-24. doi: 10.1016/0006-2952(92)90532-n. Biochem Pharmacol. 1992. PMID: 1417955

3

Vacuolar acidification and chloroquine sensitivity in Plasmodium falciparum.

Bray PG, Howells RE, Ward SA. Bray PG, et al. Among authors: ward sa. Biochem Pharmacol. 1992 Mar 17;43(6):1219-27. doi: 10.1016/0006-2952(92)90495-5. Biochem Pharmacol. 1992. PMID: 1562274

4

Current views on the mechanisms of resistance to quinoline-containing drugs in Plasmodium falciparum.

Ward SA, Bray PG, Mungthin M, Hawley SR. Ward SA, et al. Ann Trop Med Parasitol. 1995 Apr;89(2):121-4. doi: 10.1080/00034983.1995.11812942. Ann Trop Med Parasitol. 1995. PMID: 7605121

5

The effect of chemical substitution on the metabolic activation, metabolic detoxication, and pharmacological activity of amodiaquine in the mouse.

Ruscoe JE, Jewell H, Maggs JL, O'Neill PM, Storr RC, Ward SA, Park BK. Ruscoe JE, et al. Among authors: ward sa. J Pharmacol Exp Ther. 1995 Apr;273(1):393-404. J Pharmacol Exp Ther. 1995. PMID: 7714794

6

Chloroquine resistance of Plasmodium falciparum: further evidence for a lack of association with mutations of the pfmdr1 gene.

Haruki K, Bray PG, Ward SA, Hommel M, Ritchie GY. Haruki K, et al. Among authors: ward sa. Trans R Soc Trop Med Hyg. 1994 Nov-Dec;88(6):694. doi: 10.1016/0035-9203(94)90234-8. Trans R Soc Trop Med Hyg. 1994. PMID: 7886776 No abstract available.

7

The effect of fluorine substitution on the metabolism and antimalarial activity of amodiaquine.

O'Neill PM, Harrison AC, Storr RC, Hawley SR, Ward SA, Park BK. O'Neill PM, et al. Among authors: ward sa. J Med Chem. 1994 Apr 29;37(9):1362-70. doi: 10.1021/jm00035a017. J Med Chem. 1994. PMID: 8176713

8

Relationship of global chloroquine transport and reversal of resistance in Plasmodium falciparum.

Bray PG, Boulter MK, Ritchie GY, Howells RE, Ward SA. Bray PG, et al. Among authors: ward sa. Mol Biochem Parasitol. 1994 Jan;63(1):87-94. doi: 10.1016/0166-6851(94)90011-6. Mol Biochem Parasitol. 1994. PMID: 8183326

9

The potential of desipramine to reverse chloroquine resistance of Plasmodium falciparum is reduced by its binding to plasma protein.

Boulter MK, Bray PG, Howells RE, Ward SA. Boulter MK, et al. Among authors: ward sa. Trans R Soc Trop Med Hyg. 1993 May-Jun;87(3):303. doi: 10.1016/0035-9203(93)90137-f. Trans R Soc Trop Med Hyg. 1993. PMID: 8236399 No abstract available.

10

Malaria chemotherapy: resistance to quinoline containing drugs in Plasmodium falciparum.

Bray PG, Ward SA. Bray PG, et al. Among authors: ward sa. FEMS Microbiol Lett. 1993 Oct 1;113(1):1-7. doi: 10.1111/j.1574-6968.1993.tb06479.x. FEMS Microbiol Lett. 1993. PMID: 8243975 Review.

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