Sköld C - Search Results

1

Angiotensin II pseudopeptides containing 1,3,5-trisubstituted benzene scaffolds with high AT2 receptor affinity.

Georgsson J, Sköld C, Plouffe B, Lindeberg G, Botros M, Larhed M, Nyberg F, Gallo-Payet N, Gogoll A, Karlén A, Hallberg A. Georgsson J, et al. Among authors: skold c. J Med Chem. 2005 Oct 20;48(21):6620-31. doi: 10.1021/jm050280z. J Med Chem. 2005. PMID: 16220978

2

Synthesis and AT2 receptor-binding properties of angiotensin II analogues.

Rosenström U, Sköld C, Lindeberg G, Botros M, Nyberg F, Hallberg A, Karlén A. Rosenström U, et al. Among authors: skold c. J Pept Res. 2004 Nov;64(5):194-201. doi: 10.1111/j.1399-3011.2004.00184.x. J Pept Res. 2004. PMID: 15485557

3

A selective AT2 receptor ligand with a gamma-turn-like mimetic replacing the amino acid residues 4-5 of angiotensin II.

Rosenström U, Sköld C, Lindeberg G, Botros M, Nyberg F, Karlén A, Hallberg A. Rosenström U, et al. Among authors: skold c. J Med Chem. 2004 Feb 12;47(4):859-70. doi: 10.1021/jm030921v. J Med Chem. 2004. PMID: 14761188

4

New selective AT2 receptor ligands encompassing a gamma-turn mimetic replacing the amino acid residues 4-5 of angiotensin II act as agonists.

Rosenström U, Sköld C, Plouffe B, Beaudry H, Lindeberg G, Botros M, Nyberg F, Wolf G, Karlén A, Gallo-Payet N, Hallberg A. Rosenström U, et al. Among authors: skold c. J Med Chem. 2005 Jun 16;48(12):4009-24. doi: 10.1021/jm0491492. J Med Chem. 2005. PMID: 15943474

5

Design, synthesis, and incorporation of a beta-turn mimetic in angiotensin II forming novel pseudopeptides with affinity for AT1 and AT2 receptors.

Rosenström U, Sköld C, Lindeberg G, Botros M, Nyberg F, Karlén A, Hallberg A. Rosenström U, et al. Among authors: skold c. J Med Chem. 2006 Oct 5;49(20):6133-7. doi: 10.1021/jm051222g. J Med Chem. 2006. PMID: 17004728

6

Development of CoMFA models of affinity and selectivity to angiotensin II type-1 and type-2 receptors.

Sköld C, Karlén A. Sköld C, et al. J Mol Graph Model. 2007 Jul;26(1):145-53. doi: 10.1016/j.jmgm.2006.10.004. Epub 2006 Oct 26. J Mol Graph Model. 2007. PMID: 17161636

7

Synthesis of a new class of druglike angiotensin II C-terminal mimics with affinity for the AT2 receptor.

Georgsson J, Sköld C, Botros M, Lindeberg G, Nyberg F, Karlén A, Hallberg A, Larhed M. Georgsson J, et al. Among authors: skold c. J Med Chem. 2007 Apr 5;50(7):1711-5. doi: 10.1021/jm0613469. Epub 2007 Mar 15. J Med Chem. 2007. PMID: 17358051

8

Modeling binding modes of angiotensin II and pseudopeptide analogues to the AT2 receptor.

Sköld C, Nikiforovich G, Karlén A. Sköld C, et al. J Mol Graph Model. 2008 Feb;26(6):991-1003. doi: 10.1016/j.jmgm.2007.08.005. Epub 2007 Aug 26. J Mol Graph Model. 2008. PMID: 17936050

9

Discovery of dipeptides with high affinity to the specific binding site for substance P1-7.

Fransson R, Botros M, Sköld C, Nyberg F, Lindeberg G, Hallberg M, Sandström A. Fransson R, et al. Among authors: skold c. J Med Chem. 2010 Mar 25;53(6):2383-9. doi: 10.1021/jm901352b. J Med Chem. 2010. PMID: 20178322

10

From the first selective non-peptide AT(2) receptor agonist to structurally related antagonists.

Murugaiah AM, Wu X, Wallinder C, Mahalingam AK, Wan Y, Sköld C, Botros M, Guimond MO, Joshi A, Nyberg F, Gallo-Payet N, Hallberg A, Alterman M. Murugaiah AM, et al. Among authors: skold c. J Med Chem. 2012 Mar 8;55(5):2265-78. doi: 10.1021/jm2015099. Epub 2012 Feb 22. J Med Chem. 2012. PMID: 22248302

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