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Targeted inhibition of p38alpha MAPK suppresses tumor-associated endothelial cell migration in response to hypericin-based photodynamic therapy.
Hendrickx N, Dewaele M, Buytaert E, Marsboom G, Janssens S, Van Boven M, Vandenheede JR, de Witte P, Agostinis P. Hendrickx N, et al. Among authors: vandenheede jr. Biochem Biophys Res Commun. 2005 Nov 25;337(3):928-35. doi: 10.1016/j.bbrc.2005.09.135. Epub 2005 Sep 30. Biochem Biophys Res Commun. 2005. PMID: 16214108
Hypericin-induced photosensitization of HeLa cells leads to apoptosis or necrosis. Involvement of cytochrome c and procaspase-3 activation in the mechanism of apoptosis.
Vantieghem A, Assefa Z, Vandenabeele P, Declercq W, Courtois S, Vandenheede JR, Merlevede W, de Witte P, Agostinis P. Vantieghem A, et al. Among authors: vandenheede jr. FEBS Lett. 1998 Nov 27;440(1-2):19-24. doi: 10.1016/s0014-5793(98)01416-1. FEBS Lett. 1998. PMID: 9862416 Free article.
The activation of the c-Jun N-terminal kinase and p38 mitogen-activated protein kinase signaling pathways protects HeLa cells from apoptosis following photodynamic therapy with hypericin.
Assefa Z, Vantieghem A, Declercq W, Vandenabeele P, Vandenheede JR, Merlevede W, de Witte P, Agostinis P. Assefa Z, et al. Among authors: vandenheede jr. J Biol Chem. 1999 Mar 26;274(13):8788-96. doi: 10.1074/jbc.274.13.8788. J Biol Chem. 1999. PMID: 10085120 Free article.
111 results