Hoelzer D - Search Results

1

In vivo drug-response in patients with leukemic non-Hodgkin's lymphomas is associated with in vitro chemosensitivity and gene expression profiling.

Chow KU, Nowak D, Kim SZ, Schneider B, Komor M, Boehrer S, Mitrou PS, Hoelzer D, Weidmann E, Hofmann WK. Chow KU, et al. Among authors: hoelzer d. Pharmacol Res. 2006 Jan;53(1):49-61. doi: 10.1016/j.phrs.2005.09.001. Epub 2005 Oct 5. Pharmacol Res. 2006. PMID: 16213748

2

Expression of Daxx sensitizes Jurkat T-cells to the apoptosis-inducing effect of chemotherapeutic agents.

Boehrer S, Nowak D, Kukoc-Zivojnov N, Hochmuth S, Kim SZ, Hoelzer D, Mitrou PS, Weidmann E, Chow KU. Boehrer S, et al. Among authors: hoelzer d. Pharmacol Res. 2005 Apr;51(4):367-74. doi: 10.1016/j.phrs.2004.10.011. Pharmacol Res. 2005. PMID: 15683751

3

Anti-CD20 antibody (IDEC-C2B8, rituximab) enhances efficacy of cytotoxic drugs on neoplastic lymphocytes in vitro: role of cytokines, complement, and caspases.

Chow KU, Sommerlad WD, Boehrer S, Schneider B, Seipelt G, Rummel MJ, Hoelzer D, Mitrou PS, Weidmann E. Chow KU, et al. Among authors: hoelzer d. Haematologica. 2002 Jan;87(1):33-43. Haematologica. 2002. PMID: 11801463

4

In vitro studies with bendamustine: enhanced activity in combination with rituximab.

Rummel MJ, Chow KU, Hoelzer D, Mitrou PS, Weidmann E. Rummel MJ, et al. Among authors: hoelzer d. Semin Oncol. 2002 Aug;29(4 Suppl 13):12-4. doi: 10.1053/sonc.2002.34873. Semin Oncol. 2002. PMID: 12170426

5

In vitro induction of apoptosis of neoplastic cells in low-grade non-Hodgkin's lymphomas using combinations of established cytotoxic drugs with bendamustine.

Chow KU, Boehrer S, Geduldig K, Krapohl A, Hoelzer D, Mitrou PS, Weidmann E. Chow KU, et al. Among authors: hoelzer d. Haematologica. 2001 May;86(5):485-93. Haematologica. 2001. PMID: 11410411

6

Synergistic effects of chemotherapeutic drugs in lymphoma cells are associated with down-regulation of inhibitor of apoptosis proteins (IAPs), prostate-apoptosis-response-gene 4 (Par-4), death-associated protein (Daxx) and with enforced caspase activation.

Chow KU, Nowak D, Boehrer S, Ruthardt M, Knau A, Hoelzer D, Mitrou PS, Weidmann E. Chow KU, et al. Among authors: hoelzer d. Biochem Pharmacol. 2003 Sep 1;66(5):711-24. doi: 10.1016/s0006-2952(03)00410-6. Biochem Pharmacol. 2003. PMID: 12948851

7

Malignancy: Current Clinical Practice: Current Therapeutic Options in Myelodysplastic Syndromes.

Hofmann WK, Hoelzer D. Hofmann WK, et al. Among authors: hoelzer d. Hematology. 1999;4(2):91-112. doi: 10.1080/10245332.1999.11746435. Hematology. 1999. PMID: 11399556 Free article.

8

Mechanisms of resistance to STI571 (Imatinib) in Philadelphia-chromosome positive acute lymphoblastic leukemia.

Hofmann WK, Komor M, Hoelzer D, Ottmann OG. Hofmann WK, et al. Among authors: hoelzer d. Leuk Lymphoma. 2004 Apr;45(4):655-60. doi: 10.1080/10428190310001625755. Leuk Lymphoma. 2004. PMID: 15160936 Review.

9

In bcr-abl-positive myeloid cells resistant to conventional chemotherapeutic agents, expression of Par-4 increases sensitivity to imatinib (STI571) and histone deacetylase-inhibitors.

Brieger A, Boehrer S, Schaaf S, Nowak D, Ruthardt M, Kim SZ, Atadja P, Hoelzer D, Mitrou PS, Weidmann E, Chow KU. Brieger A, et al. Among authors: hoelzer d. Biochem Pharmacol. 2004 Jul 1;68(1):85-93. doi: 10.1016/j.bcp.2004.02.028. Biochem Pharmacol. 2004. PMID: 15183120

10

Prostate apoptosis response gene-4 (par-4) abrogates the survival function of p185(BCR-ABL) in hematopoietic cells.

Kukoc-Zivojnov N, Puccetti E, Chow KU, Bergmann M, Ruthardt M, Hoelzer D, Mitrou PS, Weidmann E, Boehrer S. Kukoc-Zivojnov N, et al. Among authors: hoelzer d. Exp Hematol. 2004 Jul;32(7):649-56. doi: 10.1016/j.exphem.2004.04.004. Exp Hematol. 2004. PMID: 15246161 Free article.

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