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Molecular evolution perspectives on intraspecific lateral DNA transfer of topoisomerase and gyrase loci in Streptococcus pneumoniae, with implications for fluoroquinolone resistance development and spread.
Stanhope MJ, Walsh SL, Becker JA, Italia MJ, Ingraham KA, Gwynn MN, Mathie T, Poupard JA, Miller LA, Brown JR, Amrine-Madsen H. Stanhope MJ, et al. Among authors: gwynn mn. Antimicrob Agents Chemother. 2005 Oct;49(10):4315-26. doi: 10.1128/AAC.49.10.4315-4326.2005. Antimicrob Agents Chemother. 2005. PMID: 16189113 Free PMC article.
Structural basis of DNA gyrase inhibition by antibacterial QPT-1, anticancer drug etoposide and moxifloxacin.
Chan PF, Srikannathasan V, Huang J, Cui H, Fosberry AP, Gu M, Hann MM, Hibbs M, Homes P, Ingraham K, Pizzollo J, Shen C, Shillings AJ, Spitzfaden CE, Tanner R, Theobald AJ, Stavenger RA, Bax BD, Gwynn MN. Chan PF, et al. Among authors: gwynn mn. Nat Commun. 2015 Dec 7;6:10048. doi: 10.1038/ncomms10048. Nat Commun. 2015. PMID: 26640131 Free PMC article.
Genomic approaches to antibacterial discovery.
Payne DJ, Gwynn MN, Holmes DJ, Rosenberg M. Payne DJ, et al. Among authors: gwynn mn. Methods Mol Biol. 2004;266:231-59. doi: 10.1385/1-59259-763-7:231. Methods Mol Biol. 2004. PMID: 15148422
Challenges of antibacterial discovery revisited.
Gwynn MN, Portnoy A, Rittenhouse SF, Payne DJ. Gwynn MN, et al. Ann N Y Acad Sci. 2010 Dec;1213:5-19. doi: 10.1111/j.1749-6632.2010.05828.x. Epub 2010 Nov 8. Ann N Y Acad Sci. 2010. PMID: 21058956 Review.
33 results