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Page 1
Molecular evolution perspectives on intraspecific lateral DNA transfer of topoisomerase and gyrase loci in Streptococcus pneumoniae, with implications for fluoroquinolone resistance development and spread.
Stanhope MJ, Walsh SL, Becker JA, Italia MJ, Ingraham KA, Gwynn MN, Mathie T, Poupard JA, Miller LA, Brown JR, Amrine-Madsen H. Stanhope MJ, et al. Among authors: brown jr. Antimicrob Agents Chemother. 2005 Oct;49(10):4315-26. doi: 10.1128/AAC.49.10.4315-4326.2005. Antimicrob Agents Chemother. 2005. PMID: 16189113 Free PMC article.
Bacterial resistance to leucyl-tRNA synthetase inhibitor GSK2251052 develops during treatment of complicated urinary tract infections.
O'Dwyer K, Spivak AT, Ingraham K, Min S, Holmes DJ, Jakielaszek C, Rittenhouse S, Kwan AL, Livi GP, Sathe G, Thomas E, Van Horn S, Miller LA, Twynholm M, Tomayko J, Dalessandro M, Caltabiano M, Scangarella-Oman NE, Brown JR. O'Dwyer K, et al. Among authors: brown jr. Antimicrob Agents Chemother. 2015 Jan;59(1):289-98. doi: 10.1128/AAC.03774-14. Epub 2014 Oct 27. Antimicrob Agents Chemother. 2015. PMID: 25348524 Free PMC article. Clinical Trial.
Variable sensitivity to bacterial methionyl-tRNA synthetase inhibitors reveals subpopulations of Streptococcus pneumoniae with two distinct methionyl-tRNA synthetase genes.
Gentry DR, Ingraham KA, Stanhope MJ, Rittenhouse S, Jarvest RL, O'Hanlon PJ, Brown JR, Holmes DJ. Gentry DR, et al. Among authors: brown jr. Antimicrob Agents Chemother. 2003 Jun;47(6):1784-9. doi: 10.1128/AAC.47.6.1784-1789.2003. Antimicrob Agents Chemother. 2003. PMID: 12760849 Free PMC article.
In Vitro Activity and Microbiological Efficacy of Gepotidacin from a Phase 2, Randomized, Multicenter, Dose-Ranging Study in Patients with Acute Bacterial Skin and Skin Structure Infections.
Scangarella-Oman NE, Ingraham KA, Tiffany CA, Tomsho L, Van Horn SF, Mayhew DN, Perry CR, Ashton TC, Dumont EF, Huang J, Brown JR, Miller LA. Scangarella-Oman NE, et al. Among authors: brown jr. Antimicrob Agents Chemother. 2020 Feb 21;64(3):e01302-19. doi: 10.1128/AAC.01302-19. Print 2020 Feb 21. Antimicrob Agents Chemother. 2020. PMID: 31818823 Free PMC article.
Microbiome changes in healthy volunteers treated with GSK1322322, a novel antibiotic targeting bacterial peptide deformylase.
Arat S, Spivak A, Van Horn S, Thomas E, Traini C, Sathe G, Livi GP, Ingraham K, Jones L, Aubart K, Holmes DJ, Naderer O, Brown JR. Arat S, et al. Among authors: brown jr. Antimicrob Agents Chemother. 2015 Feb;59(2):1182-92. doi: 10.1128/AAC.04506-14. Epub 2014 Dec 8. Antimicrob Agents Chemother. 2015. PMID: 25487798 Free PMC article. Clinical Trial.
3,898 results