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High resolution structures of highly bulged viral epitopes bound to major histocompatibility complex class I. Implications for T-cell receptor engagement and T-cell immunodominance.
Tynan FE, Borg NA, Miles JJ, Beddoe T, El-Hassen D, Silins SL, van Zuylen WJ, Purcell AW, Kjer-Nielsen L, McCluskey J, Burrows SR, Rossjohn J. Tynan FE, et al. Among authors: silins sl. J Biol Chem. 2005 Jun 24;280(25):23900-9. doi: 10.1074/jbc.M503060200. Epub 2005 Apr 22. J Biol Chem. 2005. PMID: 15849183 Free article.
CTL recognition of a bulged viral peptide involves biased TCR selection.
Miles JJ, Elhassen D, Borg NA, Silins SL, Tynan FE, Burrows JM, Purcell AW, Kjer-Nielsen L, Rossjohn J, Burrows SR, McCluskey J. Miles JJ, et al. Among authors: silins sl. J Immunol. 2005 Sep 15;175(6):3826-34. doi: 10.4049/jimmunol.175.6.3826. J Immunol. 2005. PMID: 16148129
Cross-reactive memory T cells for Epstein-Barr virus augment the alloresponse to common human leukocyte antigens: degenerate recognition of major histocompatibility complex-bound peptide by T cells and its role in alloreactivity.
Burrows SR, Silins SL, Khanna R, Burrows JM, Rischmueller M, McCluskey J, Moss DJ. Burrows SR, et al. Among authors: silins sl. Eur J Immunol. 1997 Jul;27(7):1726-36. doi: 10.1002/eji.1830270720. Eur J Immunol. 1997. PMID: 9247584
33 results