Engels LG - Search Results

1

The pharmacokinetic effect of discontinuation of mesalazine on mercaptopurine metabolite levels in inflammatory bowel disease patients.

Gilissen LP, Bierau J, Derijks LJ, Bos LP, Hooymans PM, van Gennip A, Stockbrügger RW, Engels LG. Gilissen LP, et al. Among authors: engels lg. Aliment Pharmacol Ther. 2005 Oct 1;22(7):605-11. doi: 10.1111/j.1365-2036.2005.02630.x. Aliment Pharmacol Ther. 2005. PMID: 16181300 Clinical Trial.

2

6-Thioguanine seems promising in azathioprine- or 6-mercaptopurine-intolerant inflammatory bowel disease patients: a short-term safety assessment.

Derijks LJ, de Jong DJ, Gilissen LP, Engels LG, Hooymans PM, Jansen JB, Mulder CJ. Derijks LJ, et al. Among authors: engels lg. Eur J Gastroenterol Hepatol. 2003 Jan;15(1):63-7. doi: 10.1097/00042737-200301000-00011. Eur J Gastroenterol Hepatol. 2003. PMID: 12544696 Clinical Trial.

3

Pharmacokinetics of 6-mercaptopurine in patients with inflammatory bowel disease: implications for therapy.

Derijks LJ, Gilissen LP, Engels LG, Bos LP, Bus PJ, Lohman JJ, Curvers WL, Van Deventer SJ, Hommes DW, Hooymans PM. Derijks LJ, et al. Among authors: engels lg. Ther Drug Monit. 2004 Jun;26(3):311-8. doi: 10.1097/00007691-200406000-00016. Ther Drug Monit. 2004. PMID: 15167634 Clinical Trial.

4

Some cases demonstrating the clinical usefulness of therapeutic drug monitoring in thiopurine-treated inflammatory bowel disease patients.

Gilissen LP, Derijks LJ, Bos LP, Verhoeven HM, Bus PJ, Hooymans PM, Engels LG. Gilissen LP, et al. Among authors: engels lg. Eur J Gastroenterol Hepatol. 2004 Jul;16(7):705-10. doi: 10.1097/01.meg.0000108333.52416.63. Eur J Gastroenterol Hepatol. 2004. PMID: 15201586

5

Pharmacokinetics of 6-thioguanine in patients with inflammatory bowel disease.

Derijks LJ, Gilissen LP, Engels LG, Bos LP, Bus PJ, Lohman JJ, van Deventer SJ, Hommes DW, Hooymans PM. Derijks LJ, et al. Among authors: engels lg. Ther Drug Monit. 2006 Feb;28(1):45-50. doi: 10.1097/01.ftd.0000179839.71138.6d. Ther Drug Monit. 2006. PMID: 16418693 Clinical Trial.

6

Pancytopenia due to high 6-methylmercaptopurine levels in a 6-mercaptopurine treated patient with Crohn's disease.

Gilissen LP, Derijks LJ, Verhoeven HM, Bierau J, Hooymans PM, Hommes DW, Engels LG. Gilissen LP, et al. Among authors: engels lg. Dig Liver Dis. 2007 Feb;39(2):182-6. doi: 10.1016/j.dld.2006.05.026. Epub 2006 Aug 1. Dig Liver Dis. 2007. PMID: 16880012

7

Toxicity of 6-thioguanine: no hepatotoxicity in a series of IBD patients treated with long-term, low dose 6-thioguanine. Some evidence for dose or metabolite level dependent effects?

Gilissen LP, Derijks LJ, Driessen A, Bos LP, Hooymans PM, Stockbrügger RW, Engels LG. Gilissen LP, et al. Among authors: engels lg. Dig Liver Dis. 2007 Feb;39(2):156-9. doi: 10.1016/j.dld.2006.10.007. Epub 2006 Dec 26. Dig Liver Dis. 2007. PMID: 17188950

8

Therapeutic drug monitoring in patients with inflammatory bowel disease and established azathioprine therapy.

Gilissen LP, Derijks LJ, Bos LP, Bus PJ, Hooymans PM, Engels LG. Gilissen LP, et al. Among authors: engels lg. Clin Drug Investig. 2004;24(8):479-86. doi: 10.2165/00044011-200424080-00006. Clin Drug Investig. 2004. PMID: 17523708

9

Absence of nodular regenerative hyperplasia after low-dose 6-thioguanine maintenance therapy in inflammatory bowel disease patients.

de Boer NK, Zondervan PE, Gilissen LP, den Hartog G, Westerveld BD, Derijks LJ, Bloemena E, Engels LG, van Bodegraven AA, Mulder CJ. de Boer NK, et al. Among authors: engels lg. Dig Liver Dis. 2008 Feb;40(2):108-13. doi: 10.1016/j.dld.2007.10.013. Epub 2007 Dec 20. Dig Liver Dis. 2008. PMID: 18083079 Clinical Trial.

10

The pharmacokinetic effect of adalimumab on thiopurine metabolism in Crohn's disease patients.

Wong DR, Pierik M, Seinen ML, van Bodegraven AA, Gilissen LP, Bus P, Bakker JA, Masclee AA, Neef C, Engels LG, Hooymans PM. Wong DR, et al. Among authors: engels lg. J Crohns Colitis. 2014 Feb;8(2):120-8. doi: 10.1016/j.crohns.2013.07.004. Epub 2013 Aug 7. J Crohns Colitis. 2014. PMID: 23932783

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