Rohr J - Search Results

1

Deciphering the late steps in the biosynthesis of the anti-tumour indolocarbazole staurosporine: sugar donor substrate flexibility of the StaG glycosyltransferase.

Salas AP, Zhu L, Sánchez C, Braña AF, Rohr J, Méndez C, Salas JA. Salas AP, et al. Among authors: rohr j. Mol Microbiol. 2005 Oct;58(1):17-27. doi: 10.1111/j.1365-2958.2005.04777.x. Mol Microbiol. 2005. PMID: 16164546 Free PMC article.

2

The biosynthetic gene cluster for the antitumor rebeccamycin: characterization and generation of indolocarbazole derivatives.

Sánchez C, Butovich IA, Braña AF, Rohr J, Méndez C, Salas JA. Sánchez C, et al. Among authors: rohr j. Chem Biol. 2002 Apr;9(4):519-31. doi: 10.1016/s1074-5521(02)00126-6. Chem Biol. 2002. PMID: 11983340

3

Tailoring modification of deoxysugars during biosynthesis of the antitumour drug chromomycin A by Streptomyces griseus ssp. griseus.

Menéndez N, Nur-E-Alam M, Braña AF, Rohr J, Salas JA, Méndez C. Menéndez N, et al. Among authors: rohr j. Mol Microbiol. 2004 Aug;53(3):903-15. doi: 10.1111/j.1365-2958.2004.04166.x. Mol Microbiol. 2004. PMID: 15255901 Free article.

4

Combinatorial biosynthesis of antitumor indolocarbazole compounds.

Sánchez C, Zhu L, Braña AF, Salas AP, Rohr J, Méndez C, Salas JA. Sánchez C, et al. Among authors: rohr j. Proc Natl Acad Sci U S A. 2005 Jan 11;102(2):461-6. doi: 10.1073/pnas.0407809102. Epub 2004 Dec 29. Proc Natl Acad Sci U S A. 2005. PMID: 15625109 Free PMC article.

5

Combining sugar biosynthesis genes for the generation of L- and D-amicetose and formation of two novel antitumor tetracenomycins.

Pérez M, Lombó F, Zhu L, Gibson M, Braña AF, Rohr J, Salas JA, Méndez C. Pérez M, et al. Among authors: rohr j. Chem Commun (Camb). 2005 Mar 28;(12):1604-6. doi: 10.1039/b417815g. Epub 2005 Jan 27. Chem Commun (Camb). 2005. PMID: 15770274

6

Deoxysugar transfer during chromomycin A3 biosynthesis in Streptomyces griseus subsp. griseus: new derivatives with antitumor activity.

Menéndez N, Nur-e-Alam M, Fischer C, Braña AF, Salas JA, Rohr J, Méndez C. Menéndez N, et al. Among authors: rohr j. Appl Environ Microbiol. 2006 Jan;72(1):167-77. doi: 10.1128/AEM.72.1.167-177.2006. Appl Environ Microbiol. 2006. PMID: 16391039 Free PMC article.

7

Isolation, characterization, and heterologous expression of the biosynthesis gene cluster for the antitumor anthracycline steffimycin.

Gullón S, Olano C, Abdelfattah MS, Braña AF, Rohr J, Méndez C, Salas JA. Gullón S, et al. Among authors: rohr j. Appl Environ Microbiol. 2006 Jun;72(6):4172-83. doi: 10.1128/AEM.00734-06. Appl Environ Microbiol. 2006. PMID: 16751529 Free PMC article.

8

Combinatorial biosynthesis of antitumor deoxysugar pathways in Streptomyces griseus: Reconstitution of "unnatural natural gene clusters" for the biosynthesis of four 2,6-D-dideoxyhexoses.

Pérez M, Lombó F, Baig I, Braña AF, Rohr J, Salas JA, Méndez C. Pérez M, et al. Among authors: rohr j. Appl Environ Microbiol. 2006 Oct;72(10):6644-52. doi: 10.1128/AEM.01266-06. Appl Environ Microbiol. 2006. PMID: 17021216 Free PMC article.

9

Biosynthesis of elloramycin in Streptomyces olivaceus requires glycosylation by enzymes encoded outside the aglycon cluster.

Ramos A, Lombó F, Braña AF, Rohr J, Méndez C, Salas JA. Ramos A, et al. Among authors: rohr j. Microbiology (Reading). 2008 Mar;154(Pt 3):781-788. doi: 10.1099/mic.0.2007/014035-0. Microbiology (Reading). 2008. PMID: 18310024 Free article.

10

Elucidation of oxygenation steps during oviedomycin biosynthesis and generation of derivatives with increased antitumor activity.

Lombó F, Abdelfattah MS, Braña AF, Salas JA, Rohr J, Méndez C. Lombó F, et al. Among authors: rohr j. Chembiochem. 2009 Jan 26;10(2):296-303. doi: 10.1002/cbic.200800425. Chembiochem. 2009. PMID: 18988223 Free PMC article.

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