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Quantitative analysis of gene regulation by seven clinically relevant progestins suggests a highly similar mechanism of action through progesterone receptors in T47D breast cancer cells.
Bray JD, Jelinsky S, Ghatge R, Bray JA, Tunkey C, Saraf K, Jacobsen BM, Richer JK, Brown EL, Winneker RC, Horwitz KB, Lyttle CR. Bray JD, et al. Among authors: winneker rc. J Steroid Biochem Mol Biol. 2005 Dec;97(4):328-41. doi: 10.1016/j.jsbmb.2005.06.032. Epub 2005 Sep 12. J Steroid Biochem Mol Biol. 2005. PMID: 16157482
Molecular and pharmacological properties of a potent and selective novel nonsteroidal progesterone receptor agonist tanaproget.
Zhang Z, Olland AM, Zhu Y, Cohen J, Berrodin T, Chippari S, Appavu C, Li S, Wilhem J, Chopra R, Fensome A, Zhang P, Wrobel J, Unwalla RJ, Lyttle CR, Winneker RC. Zhang Z, et al. Among authors: winneker rc. J Biol Chem. 2005 Aug 5;280(31):28468-75. doi: 10.1074/jbc.M504144200. Epub 2005 Jun 3. J Biol Chem. 2005. PMID: 15937332 Free article.
Comparison of human and rat uterine leiomyomata: identification of a dysregulated mammalian target of rapamycin pathway.
Crabtree JS, Jelinsky SA, Harris HA, Choe SE, Cotreau MM, Kimberland ML, Wilson E, Saraf KA, Liu W, McCampbell AS, Dave B, Broaddus RR, Brown EL, Kao W, Skotnicki JS, Abou-Gharbia M, Winneker RC, Walker CL. Crabtree JS, et al. Among authors: winneker rc. Cancer Res. 2009 Aug 1;69(15):6171-8. doi: 10.1158/0008-5472.CAN-08-4471. Epub 2009 Jul 21. Cancer Res. 2009. PMID: 19622772
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