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Reaction of dopa decarboxylase with alpha-methyldopa leads to an oxidative deamination producing 3,4-dihydroxyphenylacetone, an active site directed affinity label.
Bertoldi M, Dominici P, Moore PS, Maras B, Voltattorni CB. Bertoldi M, et al. Among authors: maras b. Biochemistry. 1998 May 5;37(18):6552-61. doi: 10.1021/bi9718898. Biochemistry. 1998. PMID: 9572873
As recently reported for serotonin (5-HT) [Bertoldi, M., Moore, P. S., Maras, B., Dominici, P., and Borri Voltattorni, C. (1996) J. Biol. Chem. 271, 23954-23959], the conversion of dopamine (DA) into 3,4-dihydroxyphenylacetaldehyde and ammonia catalyzed by DDC is ac …
As recently reported for serotonin (5-HT) [Bertoldi, M., Moore, P. S., Maras, B., Dominici, P., and Borri Voltattorni, C. (199 …
Mechanism-based inactivation of dopa decarboxylase by serotonin.
Bertoldi M, Moore PS, Maras B, Dominici P, Voltattorni CB. Bertoldi M, et al. Among authors: maras b. J Biol Chem. 1996 Sep 27;271(39):23954-9. doi: 10.1074/jbc.271.39.23954. J Biol Chem. 1996. PMID: 8798628 Free article.
102 results