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Page 1
A small molecule antagonist of the alpha(v)beta3 integrin suppresses MDA-MB-435 skeletal metastasis.
Harms JF, Welch DR, Samant RS, Shevde LA, Miele ME, Babu GR, Goldberg SF, Gilman VR, Sosnowski DM, Campo DA, Gay CV, Budgeon LR, Mercer R, Jewell J, Mastro AM, Donahue HJ, Erin N, Debies MT, Meehan WJ, Jones AL, Mbalaviele G, Nickols A, Christensen ND, Melly R, Beck LN, Kent J, Rader RK, Kotyk JJ, Pagel MD, Westlin WF, Griggs DW. Harms JF, et al. Among authors: griggs dw. Clin Exp Metastasis. 2004;21(2):119-28. doi: 10.1023/b:clin.0000024763.69809.64. Clin Exp Metastasis. 2004. PMID: 15168729
Targeting VLA4 integrin and CXCR2 mobilizes serially repopulating hematopoietic stem cells.
Karpova D, Rettig MP, Ritchey J, Cancilla D, Christ S, Gehrs L, Chendamarai E, Evbuomwan MO, Holt M, Zhang J, Abou-Ezzi G, Celik H, Wiercinska E, Yang W, Gao F, Eissenberg LG, Heier RF, Arnett SD, Meyers MJ, Prinsen MJ, Griggs DW, Trumpp A, Ruminski PG, Morrow DM, Bonig HB, Link DC, DiPersio JF. Karpova D, et al. Among authors: griggs dw. J Clin Invest. 2019 May 14;129(7):2745-2759. doi: 10.1172/JCI124738. J Clin Invest. 2019. PMID: 31085833 Free PMC article.
Adenovirus inhibition by peptidomimetic integrin antagonists.
Hippenmeyer PJ, Ruminski PG, Rico JG, Lu HS, Griggs DW. Hippenmeyer PJ, et al. Among authors: griggs dw. Antiviral Res. 2002 Jul;55(1):169-78. doi: 10.1016/s0166-3542(02)00021-9. Antiviral Res. 2002. PMID: 12076761
Anti-metastatic properties of RGD-peptidomimetic agents S137 and S247.
Shannon KE, Keene JL, Settle SL, Duffin TD, Nickols MA, Westlin M, Schroeter S, Ruminski PG, Griggs DW. Shannon KE, et al. Among authors: griggs dw. Clin Exp Metastasis. 2004;21(2):129-38. doi: 10.1023/b:clin.0000024764.93092.5f. Clin Exp Metastasis. 2004. PMID: 15168730
Optimization of the Urea Linker of Triazolopyridazine MMV665917 Results in a New Anticryptosporidial Lead with Improved Potency and Predicted hERG Safety Margin.
Oboh E, Schubert TJ, Teixeira JE, Stebbins EE, Miller P, Philo E, Thakellapalli H, Campbell SD, Griggs DW, Huston CD, Meyers MJ. Oboh E, et al. Among authors: griggs dw. J Med Chem. 2021 Aug 12;64(15):11729-11745. doi: 10.1021/acs.jmedchem.1c01136. Epub 2021 Aug 3. J Med Chem. 2021. PMID: 34342443 Free PMC article.
45 results