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Pantothenate kinase 4 controls skeletal muscle substrate metabolism.
Miranda-Cervantes A, Fritzen AM, Raun SH, Hodek O, Møller LLV, Johann K, Deisen L, Gregorevic P, Gudiksen A, Artati A, Adamski J, Andersen NR, Sigvardsen CM, Carl CS, Voldstedlund CT, Kjøbsted R, Hauck SM, Schjerling P, Jensen TE, Cebrian-Serrano A, Jähnert M, Gottmann P, Burtscher I, Lickert H, Pilegaard H, Schürmann A, Tschöp MH, Moritz T, Müller TD, Sylow L, Kiens B, Richter EA, Kleinert M. Miranda-Cervantes A, et al. Among authors: carl cs. Nat Commun. 2025 Jan 2;16(1):345. doi: 10.1038/s41467-024-55036-w. Nat Commun. 2025. PMID: 39746949 Free PMC article.
Skeletal muscle from TBC1D4 p.Arg684Ter variant carriers is severely insulin resistant but exhibits normal metabolic responses during exercise.
Kristensen JM, Kjøbsted R, Larsen TJ, Carl CS, Hingst JR, Onslev J, Birk JB, Thorup A, Steenberg DE, Knudsen JR, Henriksen NS, Needham EJ, Halling JF, Gudiksen A, Rundsten CF, Hanghøj KE, Stinson SE, Hoier B, Hansen CC, Jensen TE, Hellsten Y, Pilegaard H, Grarup N, Olesen J, Humphrey SJ, James DE, Pedersen ML, Richter EA, Hansen T, Jørgensen ME, Wojtaszewski JFP. Kristensen JM, et al. Among authors: carl cs. Nat Metab. 2024 Dec;6(12):2254-2266. doi: 10.1038/s42255-024-01153-1. Epub 2024 Oct 31. Nat Metab. 2024. PMID: 39482542 Free PMC article.
53 results