Synthetic muO-conotoxin MrVIB blocks TTX-resistant sodium channel NaV1.8 and has a long-lasting analgesic activity.
Bulaj G, Zhang MM, Green BR, Fiedler B, Layer RT, Wei S, Nielsen JS, Low SJ, Klein BD, Wagstaff JD, Chicoine L, Harty TP, Terlau H, Yoshikami D, Olivera BM.
Bulaj G, et al. Among authors: wagstaff jd.
Biochemistry. 2006 Jun 13;45(23):7404-14. doi: 10.1021/bi060159+.
Biochemistry. 2006.
PMID: 16752929