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Loss of NRF2 accelerates cognitive decline, exacerbates mitochondrial dysfunction, and is required for the cognitive enhancing effects of Centella asiatica during aging.
Zweig JA, Brandes MS, Brumbach BH, Caruso M, Wright KM, Quinn JF, Soumyanath A, Gray NE. Zweig JA, et al. Among authors: soumyanath a. Neurobiol Aging. 2021 Apr;100:48-58. doi: 10.1016/j.neurobiolaging.2020.11.019. Epub 2020 Dec 25. Neurobiol Aging. 2021. PMID: 33486357 Free PMC article.
Centella asiatica Alters Metabolic Pathways Associated With Alzheimer's Disease in the 5xFAD Mouse Model of ß-Amyloid Accumulation.
Speers AB, García-Jaramillo M, Feryn A, Matthews DG, Lichtenberg T, Caruso M, Wright KM, Quinn JF, Stevens JF, Maier CS, Soumyanath A, Gray NE. Speers AB, et al. Among authors: soumyanath a. Front Pharmacol. 2021 Dec 16;12:788312. doi: 10.3389/fphar.2021.788312. eCollection 2021. Front Pharmacol. 2021. PMID: 34975484 Free PMC article.
Bioanalytical method validation and application to a phase 1, double-blind, randomized pharmacokinetic trial of a standardized Centella asiatica (L.) Urban water extract product in healthy older adults.
Wright KM, Bollen M, David J, Mepham B, Alcázar Magaña A, McClure C, Maier CS, Quinn JF, Soumyanath A. Wright KM, et al. Among authors: soumyanath a. Front Pharmacol. 2023 Aug 23;14:1228030. doi: 10.3389/fphar.2023.1228030. eCollection 2023. Front Pharmacol. 2023. PMID: 37680716 Free PMC article.
52 results