Zhu R - Search Results

1

Sphingosine kinase 2 is required for modulation of lymphocyte traffic by FTY720.

Kharel Y, Lee S, Snyder AH, Sheasley-O'neill SL, Morris MA, Setiady Y, Zhu R, Zigler MA, Burcin TL, Ley K, Tung KS, Engelhard VH, Macdonald TL, Pearson-White S, Lynch KR. Kharel Y, et al. Among authors: zhu r. J Biol Chem. 2005 Nov 4;280(44):36865-72. doi: 10.1074/jbc.M506293200. Epub 2005 Aug 10. J Biol Chem. 2005. PMID: 16093248 Free article.

2

Asymmetric synthesis of conformationally constrained fingolimod analogues--discovery of an orally active sphingosine 1-phosphate receptor type-1 agonist and receptor type-3 antagonist.

Zhu R, Snyder AH, Kharel Y, Schaffter L, Sun Q, Kennedy PC, Lynch KR, Macdonald TL. Zhu R, et al. J Med Chem. 2007 Dec 13;50(25):6428-35. doi: 10.1021/jm7010172. Epub 2007 Nov 10. J Med Chem. 2007. PMID: 17994678 Free PMC article.

3

Characterization of a sphingosine 1-phosphate receptor antagonist prodrug.

Kennedy PC, Zhu R, Huang T, Tomsig JL, Mathews TP, David M, Peyruchaud O, Macdonald TL, Lynch KR. Kennedy PC, et al. Among authors: zhu r. J Pharmacol Exp Ther. 2011 Sep;338(3):879-89. doi: 10.1124/jpet.111.181552. Epub 2011 Jun 1. J Pharmacol Exp Ther. 2011. PMID: 21632869 Free PMC article.

4

N6-ethyl-2-alkynyl NECAs, selective human A3 adenosine receptor agonists.

Zhu R, Frazier CR, Linden J, Macdonald TL. Zhu R, et al. Bioorg Med Chem Lett. 2006 May 1;16(9):2416-8. doi: 10.1016/j.bmcl.2006.01.110. Epub 2006 Feb 17. Bioorg Med Chem Lett. 2006. PMID: 16487705

5

Mechanisms of trovafloxacin hepatotoxicity: studies of a model cyclopropylamine-containing system.

Sun Q, Zhu R, Foss FW Jr, Macdonald TL. Sun Q, et al. Among authors: zhu r. Bioorg Med Chem Lett. 2007 Dec 15;17(24):6682-6. doi: 10.1016/j.bmcl.2007.10.070. Epub 2007 Oct 24. Bioorg Med Chem Lett. 2007. PMID: 17976985

6

In vitro metabolism of a model cyclopropylamine to reactive intermediate: insights into trovafloxacin-induced hepatotoxicity.

Sun Q, Zhu R, Foss FW Jr, Macdonald TL. Sun Q, et al. Among authors: zhu r. Chem Res Toxicol. 2008 Mar;21(3):711-9. doi: 10.1021/tx7003085. Epub 2008 Feb 26. Chem Res Toxicol. 2008. PMID: 18298092

7

Wide-ranging predictions of new stable compounds powered by recommendation engines.

Griesemer SD, Baldassarri B, Zhu R, Shen J, Pal K, Park CW, Wolverton C. Griesemer SD, et al. Among authors: zhu r. Sci Adv. 2025 Jan 3;11(1):eadq1431. doi: 10.1126/sciadv.adq1431. Epub 2025 Jan 3. Sci Adv. 2025. PMID: 39752492

8

Basic Science and Pathogenesis.

Schwarze-Taufiq TA, Pranoto I, Hui K, Ogg J, Zhu R, Crane PK, Gray SL, Young JE. Schwarze-Taufiq TA, et al. Among authors: zhu r. Alzheimers Dement. 2024 Dec;20 Suppl 1:e092559. doi: 10.1002/alz.092559. Alzheimers Dement. 2024. PMID: 39751360

9

RBM47 as a potential therapeutic target for thyroid-associated ophthalmopathy.

Zhu R, Chen F, Wang BW, Jin Y, Yang JJ, Shi BJ, Chen YT, Jiang FG, Wang XH. Zhu R, et al. Int Immunopharmacol. 2025 Jan 1;147:113955. doi: 10.1016/j.intimp.2024.113955. Online ahead of print. Int Immunopharmacol. 2025. PMID: 39746275

10

METTL16 suppresses ferroptosis in cholangiocarcinoma by promoting ATF4 via m⁶A modification.

Zhao S, Cao J, Liang R, Peng T, Wu S, Liu Z, Wu Y, Song L, Sun C, Liu Y, Gu J, Wang L, Zhu R, Wang W, Sun Y. Zhao S, et al. Among authors: zhu r. Int J Biol Sci. 2025 Jan 1;21(1):189-203. doi: 10.7150/ijbs.97886. eCollection 2025. Int J Biol Sci. 2025. PMID: 39744432 Free PMC article.

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