Seeman P - Search Results

1

Antiparkinson concentrations of pramipexole and PHNO occupy dopamine D2(high) and D3(high) receptors.

Seeman P, Ko F, Willeit M, McCormick P, Ginovart N. Seeman P, et al. Synapse. 2005 Nov;58(2):122-8. doi: 10.1002/syn.20193. Synapse. 2005. PMID: 16088951

2

Amphetamine-sensitized animals show a marked increase in dopamine D2 high receptors occupied by endogenous dopamine, even in the absence of acute challenges.

Seeman P, Tallerico T, Ko F, Tenn C, Kapur S. Seeman P, et al. Synapse. 2002 Dec 15;46(4):235-9. doi: 10.1002/syn.10139. Synapse. 2002. PMID: 12373738

3

Dopamine displaces [3H]domperidone from high-affinity sites of the dopamine D2 receptor, but not [3H]raclopride or [3H]spiperone in isotonic medium: Implications for human positron emission tomography.

Seeman P, Tallerico T, Ko F. Seeman P, et al. Synapse. 2003 Sep 15;49(4):209-15. doi: 10.1002/syn.10232. Synapse. 2003. PMID: 12827639

4

Alcohol-withdrawn animals have a prolonged increase in dopamine D2high receptors, reversed by general anesthesia: relation to relapse?

Seeman P, Tallerico T, Ko F. Seeman P, et al. Synapse. 2004 May;52(2):77-83. doi: 10.1002/syn.20005. Synapse. 2004. PMID: 15034913

5

High-affinity states of human brain dopamine D2/3 receptors imaged by the agonist [11C]-(+)-PHNO.

Willeit M, Ginovart N, Kapur S, Houle S, Hussey D, Seeman P, Wilson AA. Willeit M, et al. Among authors: seeman p. Biol Psychiatry. 2006 Mar 1;59(5):389-94. doi: 10.1016/j.biopsych.2005.09.017. Epub 2005 Dec 20. Biol Psychiatry. 2006. PMID: 16373068

6

Antipsychotic pathway genes with expression altered in opposite direction by antipsychotics and amphetamine.

Ko F, Tallerico T, Seeman P. Ko F, et al. Among authors: seeman p. Synapse. 2006 Aug;60(2):141-51. doi: 10.1002/syn.20287. Synapse. 2006. PMID: 16715494

7

Consistent with dopamine supersensitivity, RGS9 expression is diminished in the amphetamine-treated animal model of schizophrenia and in postmortem schizophrenia brain.

Seeman P, Ko F, Jack E, Greenstein R, Dean B. Seeman P, et al. Synapse. 2007 May;61(5):303-9. doi: 10.1002/syn.20368. Synapse. 2007. PMID: 17318883

8

Increased dopamine D2(High) receptors in amphetamine-sensitized rats, measured by the agonist [(3)H](+)PHNO.

Seeman P, McCormick PN, Kapur S. Seeman P, et al. Synapse. 2007 May;61(5):263-7. doi: 10.1002/syn.20367. Synapse. 2007. PMID: 17318886

9

Dopamine D2 receptor radiotracers [(11)C](+)-PHNO and [(3)H]raclopride are indistinguishably inhibited by D2 agonists and antagonists ex vivo.

McCormick PN, Kapur S, Seeman P, Wilson AA. McCormick PN, et al. Among authors: seeman p. Nucl Med Biol. 2008 Jan;35(1):11-7. doi: 10.1016/j.nucmedbio.2007.08.005. Epub 2007 Nov 19. Nucl Med Biol. 2008. PMID: 18158938

10

Dopamine D2 receptors internalize in their low-affinity state.

Ko F, Seeman P, Sun WS, Kapur S. Ko F, et al. Among authors: seeman p. Neuroreport. 2002 Jun 12;13(8):1017-20. doi: 10.1097/00001756-200206120-00007. Neuroreport. 2002. PMID: 12060799

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