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99 results

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Page 1
Lack of involvement of type 7 phosphodiesterase in an experimental model of asthma.
Chevalier E, Lagente V, Dupont M, Fargeau H, Palazzi X, Richard V, Dassaud M, Fric M, Coupe M, Carré C, Leduc S, Bernardelli P, Vergne F, Berna P, Bertrand CP. Chevalier E, et al. Eur Respir J. 2012 Mar;39(3):582-8. doi: 10.1183/09031936.00102610. Epub 2011 Nov 16. Eur Respir J. 2012. PMID: 22088971 Free article.
Spiroquinazolinones as novel, potent, and selective PDE7 inhibitors. Part 2: Optimization of 5,8-disubstituted derivatives.
Bernardelli P, Lorthiois E, Vergne F, Oliveira C, Mafroud AK, Proust E, Pham N, Ducrot P, Moreau F, Idrissi M, Tertre A, Bertin B, Coupe M, Chevalier E, Descours A, Berlioz-Seux F, Berna P, Li M. Bernardelli P, et al. Among authors: chevalier e. Bioorg Med Chem Lett. 2004 Sep 20;14(18):4627-31. doi: 10.1016/j.bmcl.2004.07.010. Bioorg Med Chem Lett. 2004. PMID: 15324877
Discovery of thiadiazoles as a novel structural class of potent and selective PDE7 inhibitors. Part 2: metabolism-directed optimization studies towards orally bioavailable derivatives.
Vergne F, Bernardelli P, Lorthiois E, Pham N, Proust E, Oliveira C, Mafroud AK, Ducrot P, Wrigglesworth R, Berlioz-Seux F, Coleon F, Chevalier E, Moreau F, Idrissi M, Tertre A, Descours A, Berna P, Li M. Vergne F, et al. Among authors: chevalier e. Bioorg Med Chem Lett. 2004 Sep 20;14(18):4615-21. doi: 10.1016/j.bmcl.2004.07.009. Bioorg Med Chem Lett. 2004. PMID: 15324875
CXCR4 Protein Epitope Mimetic Antagonist POL5551 Disrupts Metastasis and Enhances Chemotherapy Effect in Triple-Negative Breast Cancer.
Xiang J, Hurchla MA, Fontana F, Su X, Amend SR, Esser AK, Douglas GJ, Mudalagiriyappa C, Luker KE, Pluard T, Ademuyiwa FO, Romagnoli B, Tuffin G, Chevalier E, Luker GD, Bauer M, Zimmermann J, Aft RL, Dembowsky K, Weilbaecher KN. Xiang J, et al. Among authors: chevalier e. Mol Cancer Ther. 2015 Nov;14(11):2473-85. doi: 10.1158/1535-7163.MCT-15-0252. Epub 2015 Aug 12. Mol Cancer Ther. 2015. PMID: 26269605 Free PMC article.
Multifaceted C-X-C Chemokine Receptor 4 (CXCR4) Inhibition Interferes with Anti-Vascular Endothelial Growth Factor Therapy-Induced Glioma Dissemination.
Gagner JP, Sarfraz Y, Ortenzi V, Alotaibi FM, Chiriboga LA, Tayyib AT, Douglas GJ, Chevalier E, Romagnoli B, Tuffin G, Schmitt M, Lemercier G, Dembowsky K, Zagzag D. Gagner JP, et al. Among authors: chevalier e. Am J Pathol. 2017 Sep;187(9):2080-2094. doi: 10.1016/j.ajpath.2017.04.020. Epub 2017 Jul 20. Am J Pathol. 2017. PMID: 28734730 Free PMC article.
Combined VEGF and CXCR4 antagonism targets the GBM stem cell population and synergistically improves survival in an intracranial mouse model of glioblastoma.
Barone A, Sengupta R, Warrington NM, Smith E, Wen PY, Brekken RA, Romagnoli B, Douglas G, Chevalier E, Bauer MP, Dembowsky K, Piwnica-Worms D, Rubin JB. Barone A, et al. Among authors: chevalier e. Oncotarget. 2014 Oct 30;5(20):9811-22. doi: 10.18632/oncotarget.2443. Oncotarget. 2014. PMID: 25238146 Free PMC article.
Mobilization of hematopoietic stem cells with the novel CXCR4 antagonist POL6326 (balixafortide) in healthy volunteers-results of a dose escalation trial.
Karpova D, Bräuninger S, Wiercinska E, Krämer A, Stock B, Graff J, Martin H, Wach A, Escot C, Douglas G, Romagnoli B, Chevalier E, Dembowski K, Hooftman L, Bonig H. Karpova D, et al. Among authors: chevalier e. J Transl Med. 2017 Jan 3;15(1):2. doi: 10.1186/s12967-016-1107-2. J Transl Med. 2017. PMID: 28049490 Free PMC article. Clinical Trial.
99 results