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Nrf2 is a critical modulator of the innate immune response in a model of uveitis.
Nagai N, Thimmulappa RK, Cano M, Fujihara M, Izumi-Nagai K, Kong X, Sporn MB, Kensler TW, Biswal S, Handa JT. Nagai N, et al. Among authors: biswal s. Free Radic Biol Med. 2009 Aug 1;47(3):300-6. doi: 10.1016/j.freeradbiomed.2009.04.033. Epub 2009 May 3. Free Radic Biol Med. 2009. PMID: 19410644 Free PMC article.
NRF2 plays a protective role in diabetic retinopathy in mice.
Xu Z, Wei Y, Gong J, Cho H, Park JK, Sung ER, Huang H, Wu L, Eberhart C, Handa JT, Du Y, Kern TS, Thimmulappa R, Barber AJ, Biswal S, Duh EJ. Xu Z, et al. Among authors: biswal s. Diabetologia. 2014 Jan;57(1):204-13. doi: 10.1007/s00125-013-3093-8. Epub 2013 Nov 3. Diabetologia. 2014. PMID: 24186494 Free PMC article.
Targeting Nrf2 with the triterpenoid CDDO-imidazolide attenuates cigarette smoke-induced emphysema and cardiac dysfunction in mice.
Sussan TE, Rangasamy T, Blake DJ, Malhotra D, El-Haddad H, Bedja D, Yates MS, Kombairaju P, Yamamoto M, Liby KT, Sporn MB, Gabrielson KL, Champion HC, Tuder RM, Kensler TW, Biswal S. Sussan TE, et al. Among authors: biswal s. Proc Natl Acad Sci U S A. 2009 Jan 6;106(1):250-5. doi: 10.1073/pnas.0804333106. Epub 2008 Dec 22. Proc Natl Acad Sci U S A. 2009. PMID: 19104057 Free PMC article.
587 results