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5'-nicked apurinic/apyrimidinic sites are resistant to beta-elimination by beta-polymerase and are persistent in human cultured cells after oxidative stress.
Nakamura J, La DK, Swenberg JA. Nakamura J, et al. J Biol Chem. 2000 Feb 25;275(8):5323-8. doi: 10.1074/jbc.275.8.5323. J Biol Chem. 2000. PMID: 10681505 Free article.
We recently reported high steady-state levels of AP sites in rat tissues and human liver DNA (Nakamura, J., and Swenberg, J. A. (1999) Cancer Res. 59, 2522-2526). These AP sites were predominantly cleaved 5' to the lesion. ...
We recently reported high steady-state levels of AP sites in rat tissues and human liver DNA (Nakamura, J., and Swenberg, J …
2,197 results