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Page 1
Par-4 links dopamine signaling and depression.
Park SK, Nguyen MD, Fischer A, Luke MP, Affar el B, Dieffenbach PB, Tseng HC, Shi Y, Tsai LH. Park SK, et al. Among authors: dieffenbach pb. Cell. 2005 Jul 29;122(2):275-87. doi: 10.1016/j.cell.2005.05.031. Cell. 2005. PMID: 16051151 Free article.
Matrix Remodeling Promotes Pulmonary Hypertension through Feedback Mechanoactivation of the YAP/TAZ-miR-130/301 Circuit.
Bertero T, Cottrill KA, Lu Y, Haeger CM, Dieffenbach P, Annis S, Hale A, Bhat B, Kaimal V, Zhang YY, Graham BB, Kumar R, Saggar R, Saggar R, Wallace WD, Ross DJ, Black SM, Fratz S, Fineman JR, Vargas SO, Haley KJ, Waxman AB, Chau BN, Fredenburgh LE, Chan SY. Bertero T, et al. Cell Rep. 2015 Nov 3;13(5):1016-32. doi: 10.1016/j.celrep.2015.09.049. Epub 2015 Oct 22. Cell Rep. 2015. PMID: 26565914 Free PMC article.
Arterial stiffness induces remodeling phenotypes in pulmonary artery smooth muscle cells via YAP/TAZ-mediated repression of cyclooxygenase-2.
Dieffenbach PB, Haeger CM, Coronata AMF, Choi KM, Varelas X, Tschumperlin DJ, Fredenburgh LE. Dieffenbach PB, et al. Am J Physiol Lung Cell Mol Physiol. 2017 Sep 1;313(3):L628-L647. doi: 10.1152/ajplung.00173.2017. Epub 2017 Jun 22. Am J Physiol Lung Cell Mol Physiol. 2017. PMID: 28642262 Free PMC article.
Our laboratory has recently demonstrated arterial stiffening early in experimental PH, along with evidence for a mechanobiological feedback loop by which arterial stiffening promotes further cellular remodeling behaviors (Liu F, Haeger CM, Dieffenbach PB, Sicard D, …
Our laboratory has recently demonstrated arterial stiffening early in experimental PH, along with evidence for a mechanobiological feedback …
A Novel Protective Role for Matrix Metalloproteinase-8 in the Pulmonary Vasculature.
Dieffenbach PB, Mallarino Haeger C, Rehman R, Corcoran AM, Coronata AMF, Vellarikkal SK, Chrobak I, Waxman AB, Vitali SH, Sholl LM, Padera RF, Lagares D, Polverino F, Owen CA, Fredenburgh LE. Dieffenbach PB, et al. Am J Respir Crit Care Med. 2021 Dec 15;204(12):1433-1451. doi: 10.1164/rccm.202108-1863OC. Am J Respir Crit Care Med. 2021. PMID: 34550870 Free PMC article.
Distal vessel stiffening is an early and pivotal mechanobiological regulator of vascular remodeling and pulmonary hypertension.
Liu F, Haeger CM, Dieffenbach PB, Sicard D, Chrobak I, Coronata AM, Suárez Velandia MM, Vitali S, Colas RA, Norris PC, Marinković A, Liu X, Ma J, Rose CD, Lee SJ, Comhair SA, Erzurum SC, McDonald JD, Serhan CN, Walsh SR, Tschumperlin DJ, Fredenburgh LE. Liu F, et al. Among authors: dieffenbach pb. JCI Insight. 2016 Jun 2;1(8):e86987. doi: 10.1172/jci.insight.86987. JCI Insight. 2016. PMID: 27347562 Free PMC article.
NEDD9 targets COL3A1 to promote endothelial fibrosis and pulmonary arterial hypertension.
Samokhin AO, Stephens T, Wertheim BM, Wang RS, Vargas SO, Yung LM, Cao M, Brown M, Arons E, Dieffenbach PB, Fewell JG, Matar M, Bowman FP, Haley KJ, Alba GA, Marino SM, Kumar R, Rosas IO, Waxman AB, Oldham WM, Khanna D, Graham BB, Seo S, Gladyshev VN, Yu PB, Fredenburgh LE, Loscalzo J, Leopold JA, Maron BA. Samokhin AO, et al. Among authors: dieffenbach pb. Sci Transl Med. 2018 Jun 13;10(445):eaap7294. doi: 10.1126/scitranslmed.aap7294. Sci Transl Med. 2018. PMID: 29899023 Free PMC article.
Mechanobiological Feedback in Pulmonary Vascular Disease.
Dieffenbach PB, Maracle M, Tschumperlin DJ, Fredenburgh LE. Dieffenbach PB, et al. Front Physiol. 2018 Jul 25;9:951. doi: 10.3389/fphys.2018.00951. eCollection 2018. Front Physiol. 2018. PMID: 30090065 Free PMC article. Review.
The Mechanobiology of Vascular Remodeling in the Aging Lung.
Dieffenbach PB, Aravamudhan A, Fredenburgh LE, Tschumperlin DJ. Dieffenbach PB, et al. Physiology (Bethesda). 2022 Jan 1;37(1):28-38. doi: 10.1152/physiol.00019.2021. Epub 2021 Sep 13. Physiology (Bethesda). 2022. PMID: 34514871 Free PMC article. Review.
Noncanonical role for Ku70/80 in the prevention of allergic airway inflammation via maintenance of airway epithelial cell organelle homeostasis.
Rehman R, Vijayakumar VE, Jaiswal A, Jain V, Mukherjee S, Vellarikkal SK, Dieffenbach PB, Fredenburgh LE, Prakash YS, Ghosh B, Agrawal A, Mabalirajan U. Rehman R, et al. Among authors: dieffenbach pb. Am J Physiol Lung Cell Mol Physiol. 2020 Oct 1;319(4):L728-L741. doi: 10.1152/ajplung.00522.2019. Epub 2020 Sep 2. Am J Physiol Lung Cell Mol Physiol. 2020. PMID: 32877223 Free article.
20 results