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Page 1
Triazine Inhibits Toxoplasma gondii tachyzoites in vitro and in vivo.
Mui EJ, Jacobus D, Milhous WK, Schiehser G, Hsu H, Roberts CW, Kirisits MJ, McLeod R. Mui EJ, et al. Among authors: schiehser g. Antimicrob Agents Chemother. 2005 Aug;49(8):3463-7. doi: 10.1128/AAC.49.8.3463-3467.2005. Antimicrob Agents Chemother. 2005. PMID: 16048961 Free PMC article.
Novel triazine JPC-2067-B inhibits Toxoplasma gondii in vitro and in vivo.
Mui EJ, Schiehser GA, Milhous WK, Hsu H, Roberts CW, Kirisits M, Muench S, Rice D, Dubey JP, Fowble JW, Rathod PK, Queener SF, Liu SR, Jacobus DP, McLeod R. Mui EJ, et al. Among authors: schiehser ga. PLoS Negl Trop Dis. 2008 Mar 5;2(3):e190. doi: 10.1371/journal.pntd.0000190. PLoS Negl Trop Dis. 2008. PMID: 18320016 Free PMC article.
JPC-2997, a new aminomethylphenol with high in vitro and in vivo antimalarial activities against blood stages of Plasmodium.
Birrell GW, Chavchich M, Ager AL, Shieh HM, Heffernan GD, Zhao W, Krasucki PE, Saionz KW, Terpinski J, Schiehser GA, Jacobus LR, Shanks GD, Jacobus DP, Edstein MD. Birrell GW, et al. Among authors: schiehser ga. Antimicrob Agents Chemother. 2015 Jan;59(1):170-7. doi: 10.1128/AAC.03762-14. Epub 2014 Oct 20. Antimicrob Agents Chemother. 2015. PMID: 25331702 Free PMC article.
Lead Selection of a New Aminomethylphenol, JPC-3210, for Malaria Treatment and Prevention.
Chavchich M, Birrell GW, Ager AL, MacKenzie DO, Heffernan GD, Schiehser GA, Jacobus LR, Shanks GD, Jacobus DP, Edstein MD. Chavchich M, et al. Among authors: schiehser ga. Antimicrob Agents Chemother. 2016 Apr 22;60(5):3115-8. doi: 10.1128/AAC.03066-15. Print 2016 May. Antimicrob Agents Chemother. 2016. PMID: 26856849 Free PMC article.
Characterization of the Preclinical Pharmacology of the New 2-Aminomethylphenol, JPC-3210, for Malaria Treatment and Prevention.
Birrell GW, Heffernan GD, Schiehser GA, Anderson J, Ager AL, Morales P, MacKenzie D, van Breda K, Chavchich M, Jacobus LR, Shanks GD, Jacobus DP, Edstein MD. Birrell GW, et al. Among authors: schiehser ga. Antimicrob Agents Chemother. 2018 Mar 27;62(4):e01335-17. doi: 10.1128/AAC.01335-17. Print 2018 Apr. Antimicrob Agents Chemother. 2018. PMID: 29311093 Free PMC article.
Synthesis, biological activity, and X-ray crystal structural analysis of diaryl ether inhibitors of malarial enoyl acyl carrier protein reductase. Part 1: 4'-substituted triclosan derivatives.
Freundlich JS, Anderson JW, Sarantakis D, Shieh HM, Yu M, Valderramos JC, Lucumi E, Kuo M, Jacobs WR Jr, Fidock DA, Schiehser GA, Jacobus DP, Sacchettini JC. Freundlich JS, et al. Bioorg Med Chem Lett. 2005 Dec 1;15(23):5247-52. doi: 10.1016/j.bmcl.2005.08.044. Epub 2005 Sep 29. Bioorg Med Chem Lett. 2005. PMID: 16198563
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