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Heterotrimeric G protein-independent signaling of a G protein-coupled receptor. Direct binding of ARNO/cytohesin-2 to the carboxyl terminus of the A2A adenosine receptor is necessary for sustained activation of the ERK/MAP kinase pathway.
Gsandtner I, Charalambous C, Stefan E, Ogris E, Freissmuth M, Zezula J. Gsandtner I, et al. Among authors: ogris e. J Biol Chem. 2005 Sep 9;280(36):31898-905. doi: 10.1074/jbc.M506515200. Epub 2005 Jul 18. J Biol Chem. 2005. PMID: 16027149 Free article.
Mutation-oriented profiling of autoinhibitory kinase conformations predicts RAF inhibitor efficacies.
Mayrhofer JE, Enzler F, Feichtner A, Röck R, Fleischmann J, Raffeiner A, Tschaikner P, Ogris E, Huber RG, Hartl M, Schneider R, Troppmair J, Torres-Quesada O, Stefan E. Mayrhofer JE, et al. Among authors: ogris e. Proc Natl Acad Sci U S A. 2020 Dec 8;117(49):31105-31113. doi: 10.1073/pnas.2012150117. Epub 2020 Nov 23. Proc Natl Acad Sci U S A. 2020. PMID: 33229534 Free PMC article.
M-Track: detecting short-lived protein-protein interactions in vivo.
Zuzuarregui A, Kupka T, Bhatt B, Dohnal I, Mudrak I, Friedmann C, Schüchner S, Frohner IE, Ammerer G, Ogris E. Zuzuarregui A, et al. Among authors: ogris e. Nat Methods. 2012 Jun;9(6):594-6. doi: 10.1038/nmeth.2017. Epub 2012 May 13. Nat Methods. 2012. PMID: 22581371 Free PMC article.
145 results