Leighton JL - Search Results

1

A simple and general chiral silicon Lewis acid for asymmetric synthesis: highly enantioselective [3+2] acylhydrazone-enol ether cycloadditions.

Shirakawa S, Lombardi PJ, Leighton JL. Shirakawa S, et al. Among authors: leighton jl. J Am Chem Soc. 2005 Jul 20;127(28):9974-5. doi: 10.1021/ja052307+. J Am Chem Soc. 2005. PMID: 16011341

2

Enantioselective friedel-crafts alkylations with benzoylhydrazones promoted by a simple strained silacycle reagent.

Shirakawa S, Berger R, Leighton JL. Shirakawa S, et al. Among authors: leighton jl. J Am Chem Soc. 2005 Mar 9;127(9):2858-9. doi: 10.1021/ja042522a. J Am Chem Soc. 2005. PMID: 15740114

3

An efficient asymmetric synthesis of manzacidin C.

Tran K, Lombardi PJ, Leighton JL. Tran K, et al. Among authors: leighton jl. Org Lett. 2008 Jul 17;10(14):3165-7. doi: 10.1021/ol8011869. Epub 2008 Jun 24. Org Lett. 2008. PMID: 18572947

4

Highly diastereo- and enantioselective reagents for aldehyde crotylation.

Hackman BM, Lombardi PJ, Leighton JL. Hackman BM, et al. Among authors: leighton jl. Org Lett. 2004 Nov 11;6(23):4375-7. doi: 10.1021/ol0480731. Org Lett. 2004. PMID: 15524487

5

A new silicon lewis acid for highly enantioselective mannich reactions of aliphatic ketone-derived hydrazones.

Notte GT, Leighton JL. Notte GT, et al. Among authors: leighton jl. J Am Chem Soc. 2008 May 28;130(21):6676-7. doi: 10.1021/ja800830h. Epub 2008 Apr 30. J Am Chem Soc. 2008. PMID: 18444641

6

Tandem asymmetric Aza-Darzens/ring-opening reactions: dual functionality from the silane lewis acid.

Valdez SC, Leighton JL. Valdez SC, et al. Among authors: leighton jl. J Am Chem Soc. 2009 Oct 21;131(41):14638-9. doi: 10.1021/ja9066354. J Am Chem Soc. 2009. PMID: 19778019

7

Enantioselective allylation of ketone-derived benzoylhydrazones: practical synthesis of tertiary carbinamines.

Berger R, Duff K, Leighton JL. Berger R, et al. Among authors: leighton jl. J Am Chem Soc. 2004 May 12;126(18):5686-7. doi: 10.1021/ja0486418. J Am Chem Soc. 2004. PMID: 15125659

8

Toward a versatile allylation reagent: practical, enantioselective allylation of acylhydrazones using strained silacycles.

Berger R, Rabbat PM, Leighton JL. Berger R, et al. Among authors: leighton jl. J Am Chem Soc. 2003 Aug 13;125(32):9596-7. doi: 10.1021/ja035001g. J Am Chem Soc. 2003. PMID: 12904019

9

A more comprehensive and highly practical solution to enantioselective aldehyde crotylation.

Kim H, Ho S, Leighton JL. Kim H, et al. Among authors: leighton jl. J Am Chem Soc. 2011 May 4;133(17):6517-20. doi: 10.1021/ja200712f. Epub 2011 Apr 12. J Am Chem Soc. 2011. PMID: 21486033 Free PMC article.

10

Strained silacycles in organic synthesis: a new reagent for the enantioselective allylation of aldehydes.

Kinnaird JW, Ng PY, Kubota K, Wang X, Leighton JL. Kinnaird JW, et al. Among authors: leighton jl. J Am Chem Soc. 2002 Jul 10;124(27):7920-1. doi: 10.1021/ja0264908. J Am Chem Soc. 2002. PMID: 12095334

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