Scanlan TS - Search Results

1

Selective thyroid receptor modulation by GC-1 reduces serum lipids and stimulates steps of reverse cholesterol transport in euthyroid mice.

Johansson L, Rudling M, Scanlan TS, Lundåsen T, Webb P, Baxter J, Angelin B, Parini P. Johansson L, et al. Among authors: scanlan ts. Proc Natl Acad Sci U S A. 2005 Jul 19;102(29):10297-302. doi: 10.1073/pnas.0504379102. Epub 2005 Jul 8. Proc Natl Acad Sci U S A. 2005. PMID: 16006512 Free PMC article.

2

Selective activation of thyroid hormone signaling pathways by GC-1: a new approach to controlling cholesterol and body weight.

Baxter JD, Webb P, Grover G, Scanlan TS. Baxter JD, et al. Among authors: scanlan ts. Trends Endocrinol Metab. 2004 May-Jun;15(4):154-7. doi: 10.1016/j.tem.2004.03.008. Trends Endocrinol Metab. 2004. PMID: 15109613 Review.

3

Ligand selectivity by seeking hydrophobicity in thyroid hormone receptor.

Borngraeber S, Budny MJ, Chiellini G, Cunha-Lima ST, Togashi M, Webb P, Baxter JD, Scanlan TS, Fletterick RJ. Borngraeber S, et al. Among authors: scanlan ts. Proc Natl Acad Sci U S A. 2003 Dec 23;100(26):15358-63. doi: 10.1073/pnas.2136689100. Epub 2003 Dec 12. Proc Natl Acad Sci U S A. 2003. PMID: 14673100 Free PMC article.

4

Selective modulation of thyroid hormone receptor action.

Baxter JD, Dillmann WH, West BL, Huber R, Furlow JD, Fletterick RJ, Webb P, Apriletti JW, Scanlan TS. Baxter JD, et al. Among authors: scanlan ts. J Steroid Biochem Mol Biol. 2001 Jan-Mar;76(1-5):31-42. doi: 10.1016/s0960-0760(01)00052-8. J Steroid Biochem Mol Biol. 2001. PMID: 11384861 Review.

5

Effects of the thyroid hormone receptor agonist GC-1 on metabolic rate and cholesterol in rats and primates: selective actions relative to 3,5,3'-triiodo-L-thyronine.

Grover GJ, Egan DM, Sleph PG, Beehler BC, Chiellini G, Nguyen NH, Baxter JD, Scanlan TS. Grover GJ, et al. Among authors: scanlan ts. Endocrinology. 2004 Apr;145(4):1656-61. doi: 10.1210/en.2003-0973. Epub 2003 Dec 30. Endocrinology. 2004. PMID: 14701670

6

Structure-based design and synthesis of a thyroid hormone receptor (TR) antagonist.

Baxter JD, Goede P, Apriletti JW, West BL, Feng W, Mellstrom K, Fletterick RJ, Wagner RL, Kushner PJ, Ribeiro RC, Webb P, Scanlan TS, Nilsson S. Baxter JD, et al. Among authors: scanlan ts. Endocrinology. 2002 Feb;143(2):517-24. doi: 10.1210/endo.143.2.8617. Endocrinology. 2002. PMID: 11796506

7

Hammett analysis of selective thyroid hormone receptor modulators reveals structural and electronic requirements for hormone antagonists.

Nguyen NH, Apriletti JW, Baxter JD, Scanlan TS. Nguyen NH, et al. Among authors: scanlan ts. J Am Chem Soc. 2005 Apr 6;127(13):4599-608. doi: 10.1021/ja0440093. J Am Chem Soc. 2005. PMID: 15796525

8

Different configurations of specific thyroid hormone response elements mediate opposite effects of thyroid hormone and GC-1 on gene expression.

Gloss B, Giannocco G, Swanson EA, Moriscot AS, Chiellini G, Scanlan T, Baxter JD, Dillmann WH. Gloss B, et al. Endocrinology. 2005 Nov;146(11):4926-33. doi: 10.1210/en.2005-0631. Epub 2005 Aug 4. Endocrinology. 2005. PMID: 16081636

9

Synthesis and biological activity of novel thyroid hormone analogues: 5'-aryl substituted GC-1 derivatives.

Chiellini G, Nguyen NH, Apriletti JW, Baxter JD, Scanlan TS. Chiellini G, et al. Among authors: scanlan ts. Bioorg Med Chem. 2002 Feb;10(2):333-46. doi: 10.1016/s0968-0896(01)00284-x. Bioorg Med Chem. 2002. PMID: 11741782

10

Both thyroid hormone receptor (TR)beta 1 and TR beta 2 isoforms contribute to the regulation of hypothalamic thyrotropin-releasing hormone.

Dupré SM, Guissouma H, Flamant F, Seugnet I, Scanlan TS, Baxter JD, Samarut J, Demeneix BA, Becker N. Dupré SM, et al. Among authors: scanlan ts. Endocrinology. 2004 May;145(5):2337-45. doi: 10.1210/en.2003-1209. Epub 2004 Jan 15. Endocrinology. 2004. PMID: 14726446

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