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Page 1
Benzazoles as allosteric potentiators of metabotropic glutamate receptor 2 (mGluR2): efficacy in an animal model for schizophrenia.
Govek SP, Bonnefous C, Hutchinson JH, Kamenecka T, McQuiston J, Pracitto R, Zhao LX, Gardner MF, James JK, Daggett LP, Rowe BA, Schaffhauser H, Bristow LJ, Campbell UC, Rodriguez DE, Vernier JM. Govek SP, et al. Among authors: pracitto r. Bioorg Med Chem Lett. 2005 Sep 15;15(18):4068-72. doi: 10.1016/j.bmcl.2005.06.017. Bioorg Med Chem Lett. 2005. PMID: 16005222
Identification and synthesis of [1,2,4]triazolo[3,4-a]phthalazine derivatives as high-affinity ligands to the alpha 2 delta-1 subunit of voltage gated calcium channel.
Lebsack AD, Gunzner J, Wang B, Pracitto R, Schaffhauser H, Santini A, Aiyar J, Bezverkov R, Munoz B, Liu W, Venkatraman S. Lebsack AD, et al. Among authors: pracitto r. Bioorg Med Chem Lett. 2004 May 17;14(10):2463-7. doi: 10.1016/j.bmcl.2004.03.008. Bioorg Med Chem Lett. 2004. PMID: 15109633
First-in-Human Study of 18F-SynVesT-2: An SV2A PET Imaging Probe with Fast Brain Kinetics and High Specific Binding.
Drake LR, Wu Y, Naganawa M, Asch R, Zheng C, Najafzadeh S, Pracitto R, Lindemann M, Li S, Ropchan J, Labaree D, Emery PR, Dias M, Henry S, Nabulsi N, Matuskey D, Hillmer AT, Gallezot JD, Carson RE, Cai Z, Huang Y. Drake LR, et al. Among authors: pracitto r. J Nucl Med. 2024 Feb 15;65(3):462-9. doi: 10.2967/jnumed.123.266470. Online ahead of print. J Nucl Med. 2024. PMID: 38360052 Free PMC article.
Preclinical evaluation of a brain penetrant PARP PET imaging probe in rat glioblastoma and nonhuman primates.
Chen B, Ojha DP, Toyonaga T, Tong J, Pracitto R, Thomas MA, Liu M, Kapinos M, Zhang L, Zheng MQ, Holden D, Fowles K, Ropchan J, Nabulsi N, De Feyter H, Carson RE, Huang Y, Cai Z. Chen B, et al. Among authors: pracitto r. Eur J Nucl Med Mol Imaging. 2023 Jun;50(7):2081-2099. doi: 10.1007/s00259-023-06162-y. Epub 2023 Feb 28. Eur J Nucl Med Mol Imaging. 2023. PMID: 36849748
A metabolically stable PET tracer for imaging synaptic vesicle protein 2A: synthesis and preclinical characterization of [18F]SDM-16.
Zheng C, Holden D, Zheng MQ, Pracitto R, Wilcox KC, Lindemann M, Felchner Z, Zhang L, Tong J, Fowles K, Finnema SJ, Nabulsi N, Carson RE, Huang Y, Cai Z. Zheng C, et al. Among authors: pracitto r. Eur J Nucl Med Mol Imaging. 2022 Apr;49(5):1482-1496. doi: 10.1007/s00259-021-05597-5. Epub 2021 Nov 11. Eur J Nucl Med Mol Imaging. 2022. PMID: 34761284 Free PMC article.
Further Investigation of Synaptic Vesicle Protein 2A (SV2A) Ligands Designed for Positron Emission Tomography and Single-Photon Emission Computed Tomography Imaging: Synthesis and Structure-Activity Relationship of Substituted Pyridinylmethyl-4-(3,5-difluorophenyl)pyrrolidin-2-ones.
Pracitto R, Wilcox KC, Lindemann M, Tong J, Zheng C, Li S, Finnema SJ, Huang Y, Cai Z. Pracitto R, et al. ACS Omega. 2021 Oct 8;6(42):27676-27683. doi: 10.1021/acsomega.1c02433. eCollection 2021 Oct 26. ACS Omega. 2021. PMID: 34722967 Free PMC article.
Imaging Pituitary Vasopressin 1B Receptor in Humans with the PET Radiotracer 11C-TASP699.
Naganawa M, Nabulsi NB, Matuskey D, Henry S, Ropchan J, Lin SF, Gao H, Pracitto R, Labaree D, Zhang MR, Suhara T, Nishino I, Sabia H, Ozaki S, Huang Y, Carson RE. Naganawa M, et al. Among authors: pracitto r. J Nucl Med. 2022 Apr;63(4):609-614. doi: 10.2967/jnumed.121.262430. Epub 2021 Aug 12. J Nucl Med. 2022. PMID: 34385336 Free article.
Assessment of test-retest reproducibility of [18F]SynVesT-1, a novel radiotracer for PET imaging of synaptic vesicle glycoprotein 2A.
Li S, Naganawa M, Pracitto R, Najafzadeh S, Holden D, Henry S, Matuskey D, Emery PR, Cai Z, Ropchan J, Nabulsi N, Carson RE, Huang Y. Li S, et al. Among authors: pracitto r. Eur J Nucl Med Mol Imaging. 2021 May;48(5):1327-1338. doi: 10.1007/s00259-020-05149-3. Epub 2021 Jan 8. Eur J Nucl Med Mol Imaging. 2021. PMID: 33416954
20 results