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102 results

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Evaluation of Salmonella enterica serovar Typhi (Ty2 aroC-ssaV-) M01ZH09, with a defined mutation in the Salmonella pathogenicity island 2, as a live, oral typhoid vaccine in human volunteers.
Kirkpatrick BD, McKenzie R, O'Neill JP, Larsson CJ, Bourgeois AL, Shimko J, Bentley M, Makin J, Chatfield S, Hindle Z, Fidler C, Robinson BE, Ventrone CH, Bansal N, Carpenter CM, Kutzko D, Hamlet S, LaPointe C, Taylor DN. Kirkpatrick BD, et al. Among authors: lapointe c. Vaccine. 2006 Jan 12;24(2):116-23. doi: 10.1016/j.vaccine.2005.08.008. Epub 2005 Aug 18. Vaccine. 2006. PMID: 16140433 Clinical Trial.
Discovery and Preclinical Characterization of Fulacimstat (BAY 1142524), a Potent and Selective Chymase Inhibitor As a New Profibrinolytic Approach for Safe Thrombus Resolution.
Fürstner C, Ackerstaff J, Meier H, Straub A, Mittendorf J, Schamberger J, Schäfer M, Börngen K, Jörißen H, Zubov D, Zimmermann K, Tersteegen A, Geiss V, Hartmann E, Albrecht-Küpper B, D'Orléans-Juste P, Lapointe C, Vincent L, Heitmeier S, Tinel H. Fürstner C, et al. Among authors: lapointe c. J Med Chem. 2024 Nov 14. doi: 10.1021/acs.jmedchem.4c01819. Online ahead of print. J Med Chem. 2024. PMID: 39541507
eIF1 and eIF5 dynamically control translation start site fidelity.
Grosely R, Alvarado C, Ivanov IP, Nicholson OB, Puglisi JD, Dever TE, Lapointe CP. Grosely R, et al. Among authors: lapointe cp. bioRxiv [Preprint]. 2024 Jul 13:2024.07.10.602410. doi: 10.1101/2024.07.10.602410. bioRxiv. 2024. PMID: 39026837 Free PMC article. Preprint.
Incidence and Risk Factors of Chronic Postoperative Pain in Same-day Surgery: A Prospective Cohort Study.
Boko MF, Khanna AK, D'Aragon F, Spence J, Conen D, Patel A, Ayad S, Wijeysundera DN, Choinière M, Sessler DI, Carrier FM, Harlock J, Koopman JSHA, Durand M, Bhojani N, Turan A, Pagé G, Devereaux PJ, Duceppe E; VALIANCE Study Collaborators. Boko MF, et al. Anesthesiology. 2024 Aug 1;141(2):286-299. doi: 10.1097/ALN.0000000000005030. Anesthesiology. 2024. PMID: 38669010
WindCline: Sloping wind tunnel for characterizing flame behavior under variable inclines and wind conditions.
Makowiecki AS, Coburn SC, Sheppard S, Bitterlin B, Breda T, Dawlatzai A, Giannella R, Jaros A, Kling C, Kolb E, Lapointe C, Simons-Wellin S, Michelsen HA, Daily JW, Hannigan M, Hamlington PE, Farnsworth J, Rieker GB. Makowiecki AS, et al. Among authors: lapointe c. Rev Sci Instrum. 2024 Feb 1;95(2):025103. doi: 10.1063/5.0175784. Rev Sci Instrum. 2024. PMID: 38341723
Universal features of Nsp1-mediated translational shutdown by coronaviruses.
Schubert K, Karousis ED, Ban I, Lapointe CP, Leibundgut M, Bäumlin E, Kummerant E, Scaiola A, Schönhut T, Ziegelmüller J, Puglisi JD, Mühlemann O, Ban N. Schubert K, et al. Among authors: lapointe cp. Mol Cell. 2023 Oct 5;83(19):3546-3557.e8. doi: 10.1016/j.molcel.2023.09.002. Mol Cell. 2023. PMID: 37802027 Free PMC article.
Universal features of Nsp1-mediated translational shutdown by coronaviruses.
Schubert K, Karousis ED, Ban I, Lapointe CP, Leibundgut M, Bäumlin E, Kummerant E, Scaiola A, Schönhut T, Ziegelmüller J, Puglisi JD, Mühlemann O, Ban N. Schubert K, et al. Among authors: lapointe cp. bioRxiv [Preprint]. 2023 Jun 1:2023.05.31.543022. doi: 10.1101/2023.05.31.543022. bioRxiv. 2023. Update in: Mol Cell. 2023 Oct 5;83(19):3546-3557.e8. doi: 10.1016/j.molcel.2023.09.002 PMID: 37398176 Free PMC article. Updated. Preprint.
102 results