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Page 1
Exploration of the P1 SAR of aldehyde cathepsin K inhibitors.
Catalano JG, Deaton DN, Furfine ES, Hassell AM, McFadyen RB, Miller AB, Miller LR, Shewchuk LM, Willard DH Jr, Wright LL. Catalano JG, et al. Among authors: wright ll. Bioorg Med Chem Lett. 2004 Jan 5;14(1):275-8. doi: 10.1016/j.bmcl.2003.09.088. Bioorg Med Chem Lett. 2004. PMID: 14684342
Optimization of pyrrolidinone based HIV protease inhibitors.
Sherrill RG, Andrews CW, Bock WJ, Davis-Ward RG, Furfine ES, Hazen RJ, Rutkowske RD, Spaltenstein A, Wright LL. Sherrill RG, et al. Among authors: wright ll. Bioorg Med Chem Lett. 2005 Jan 3;15(1):81-4. doi: 10.1016/j.bmcl.2004.10.029. Bioorg Med Chem Lett. 2005. PMID: 15582415
New, potent P1/P2-morpholinone-based HIV-protease inhibitors.
Kazmierski WM, Furfine E, Spaltenstein A, Wright LL. Kazmierski WM, et al. Among authors: wright ll. Bioorg Med Chem Lett. 2006 Oct 1;16(19):5226-30. doi: 10.1016/j.bmcl.2006.07.014. Epub 2006 Aug 10. Bioorg Med Chem Lett. 2006. PMID: 16904316
Discovery of a potent boronic acid derived inhibitor of the HCV RNA-dependent RNA polymerase.
Maynard A, Crosby RM, Ellis B, Hamatake R, Hong Z, Johns BA, Kahler KM, Koble C, Leivers A, Leivers MR, Mathis A, Peat AJ, Pouliot JJ, Roberts CD, Samano V, Schmidt RM, Smith GK, Spaltenstein A, Stewart EL, Thommes P, Turner EM, Voitenleitner C, Walker JT, Waitt G, Weatherhead J, Weaver K, Williams S, Wright L, Xiong ZZ, Haigh D, Shotwell JB. Maynard A, et al. J Med Chem. 2014 Mar 13;57(5):1902-13. doi: 10.1021/jm400317w. Epub 2013 May 29. J Med Chem. 2014. PMID: 23672667
Design of small molecule ketoamide-based inhibitors of cathepsin K.
Catalano JG, Deaton DN, Long ST, McFadyen RB, Miller LR, Payne JA, Wells-Knecht KJ, Wright LL. Catalano JG, et al. Among authors: wright ll. Bioorg Med Chem Lett. 2004 Feb 9;14(3):719-22. doi: 10.1016/j.bmcl.2003.11.029. Bioorg Med Chem Lett. 2004. PMID: 14741275
351 results