Ward WH - Search Results

1

Kinetic characteristics of ICI D1694: a quinazoline antifolate which inhibits thymidylate synthase.

Ward WH, Kimbell R, Jackman AL. Ward WH, et al. Biochem Pharmacol. 1992 May 8;43(9):2029-31. doi: 10.1016/0006-2952(92)90646-z. Biochem Pharmacol. 1992. PMID: 1596289

2

(2,6-Dimethylphenylsulphonyl)nitromethane: a new structural type of aldose reductase inhibitor which follows biphasic kinetics and uses an allosteric binding site.

Ward WH, Cook PN, Mirrlees DJ, Brittain DR, Preston J, Carey F, Tuffin DP, Howe R. Ward WH, et al. Biochem Pharmacol. 1991 Nov 6;42(11):2115-23. doi: 10.1016/0006-2952(91)90346-7. Biochem Pharmacol. 1991. PMID: 1958230

3

Epidermal growth factor receptor tyrosine kinase. Investigation of catalytic mechanism, structure-based searching and discovery of a potent inhibitor.

Ward WH, Cook PN, Slater AM, Davies DH, Holdgate GA, Green LR. Ward WH, et al. Biochem Pharmacol. 1994 Aug 17;48(4):659-66. doi: 10.1016/0006-2952(94)90042-6. Biochem Pharmacol. 1994. PMID: 8080438

4

Inhibition of squalene synthase in vitro by 3-(biphenyl-4-yl)-quinuclidine.

Ward WH, Holdgate GA, Freeman S, McTaggart F, Girdwood PA, Davidson RG, Mallion KB, Brown GR, Eakin MA. Ward WH, et al. Biochem Pharmacol. 1996 Jun 14;51(11):1489-501. doi: 10.1016/0006-2952(96)00090-1. Biochem Pharmacol. 1996. PMID: 8630090

5

A novel series of non-nucleoside inhibitors of inosine 5'-monophosphate dehydrogenase with immunosuppressive activity.

Franklin TJ, Morris WP, Jacobs VN, Culbert EJ, Heys CA, Ward WH, Cook PN, Jung F, Plé P. Franklin TJ, et al. Among authors: ward wh. Biochem Pharmacol. 1999 Sep 1;58(5):867-76. doi: 10.1016/s0006-2952(99)00170-7. Biochem Pharmacol. 1999. PMID: 10449198

6

Ponalrestat: a potent and specific inhibitor of aldose reductase.

Ward WH, Sennitt CM, Ross H, Dingle A, Timms D, Mirrlees DJ, Tuffin DP. Ward WH, et al. Biochem Pharmacol. 1990 Jan 15;39(2):337-46. doi: 10.1016/0006-2952(90)90033-h. Biochem Pharmacol. 1990. PMID: 2105733

7

Kinetic characteristics of ZENECA ZD5522, a potent inhibitor of human and bovine lens aldose reductase.

Cook PN, Ward WH, Petrash JM, Mirrlees DJ, Sennitt CM, Carey F, Preston J, Brittain DR, Tuffin DP, Howe R. Cook PN, et al. Among authors: ward wh. Biochem Pharmacol. 1995 Apr 18;49(8):1043-9. doi: 10.1016/0006-2952(95)98499-y. Biochem Pharmacol. 1995. PMID: 7748183

8

Inhibition of squalene synthase of rat liver by novel 3' substituted quinuclidines.

McTaggart F, Brown GR, Davidson RG, Freeman S, Holdgate GA, Mallion KB, Mirrlees DJ, Smith GJ, Ward WH. McTaggart F, et al. Among authors: ward wh. Biochem Pharmacol. 1996 Jun 14;51(11):1477-87. doi: 10.1016/0006-2952(96)00089-5. Biochem Pharmacol. 1996. PMID: 8630089

9

Inhibition of aldose reductase by (2,6-dimethylphenylsulphonyl)nitromethane: possible implications for the nature of an inhibitor binding site and a cause of biphasic kinetics.

Ward WH, Cook PN, Mirrlees DJ, Brittain DR, Preston J, Carey F, Tuffin DP, Howe R. Ward WH, et al. Adv Exp Med Biol. 1993;328:301-11. doi: 10.1007/978-1-4615-2904-0_32. Adv Exp Med Biol. 1993. PMID: 8493907

10

Kinetic and structural characteristics of the inhibition of enoyl (acyl carrier protein) reductase by triclosan.

Ward WH, Holdgate GA, Rowsell S, McLean EG, Pauptit RA, Clayton E, Nichols WW, Colls JG, Minshull CA, Jude DA, Mistry A, Timms D, Camble R, Hales NJ, Britton CJ, Taylor IW. Ward WH, et al. Biochemistry. 1999 Sep 21;38(38):12514-25. doi: 10.1021/bi9907779. Biochemistry. 1999. PMID: 10493822

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