Hammond TG - Search Results

1

Spectrum of effects detected in the rat functional observational battery following oral administration of non-CNS targeted compounds.

Redfern WS, Strang I, Storey S, Heys C, Barnard C, Lawton K, Hammond TG, Valentin JP. Redfern WS, et al. Among authors: hammond tg. J Pharmacol Toxicol Methods. 2005 Jul-Aug;52(1):77-82. doi: 10.1016/j.vascn.2005.04.005. J Pharmacol Toxicol Methods. 2005. PMID: 15936219

2

Safety and secondary pharmacology: successes, threats, challenges and opportunities.

Valentin JP, Hammond T. Valentin JP, et al. J Pharmacol Toxicol Methods. 2008 Sep-Oct;58(2):77-87. doi: 10.1016/j.vascn.2008.05.007. Epub 2008 Jun 3. J Pharmacol Toxicol Methods. 2008. PMID: 18586111 Review.

3

A framework to assess the translation of safety pharmacology data to humans.

Valentin JP, Bialecki R, Ewart L, Hammond T, Leishmann D, Lindgren S, Martinez V, Pollard C, Redfern W, Wallis R. Valentin JP, et al. J Pharmacol Toxicol Methods. 2009 Sep-Oct;60(2):152-8. doi: 10.1016/j.vascn.2009.05.011. Epub 2009 Jul 17. J Pharmacol Toxicol Methods. 2009. PMID: 19616110

4

Nonclinical proarrhythmia models: predicting Torsades de Pointes.

Lawrence CL, Pollard CE, Hammond TG, Valentin JP. Lawrence CL, et al. Among authors: hammond tg. J Pharmacol Toxicol Methods. 2005 Jul-Aug;52(1):46-59. doi: 10.1016/j.vascn.2005.04.011. J Pharmacol Toxicol Methods. 2005. PMID: 15975832 Review.

5

Correction of QT values to allow for increases in heart rate in conscious Beagle dogs in toxicology assessment.

Tattersall ML, Dymond M, Hammond T, Valentin JP. Tattersall ML, et al. J Pharmacol Toxicol Methods. 2006 Jan-Feb;53(1):11-9. doi: 10.1016/j.vascn.2005.02.005. J Pharmacol Toxicol Methods. 2006. PMID: 15886026

6

Value of non-clinical cardiac repolarization assays in supporting the discovery and development of safer medicines.

Valentin JP, Pollard C, Lainée P, Hammond T. Valentin JP, et al. Br J Pharmacol. 2010 Jan;159(1):25-33. doi: 10.1111/j.1476-5381.2009.00530.x. Br J Pharmacol. 2010. PMID: 20141518 Free PMC article. Review.

7

Review of the predictive value of the Langendorff heart model (Screenit system) in assessing the proarrhythmic potential of drugs.

Valentin JP, Hoffmann P, De Clerck F, Hammond TG, Hondeghem L. Valentin JP, et al. Among authors: hammond tg. J Pharmacol Toxicol Methods. 2004 May-Jun;49(3):171-81. doi: 10.1016/j.vascn.2004.03.008. J Pharmacol Toxicol Methods. 2004. PMID: 15172013 Review.

8

Safety pharmacology--a progressive approach.

Redfern WS, Wakefield ID, Prior H, Pollard CE, Hammond TG, Valentin JP. Redfern WS, et al. Among authors: hammond tg. Fundam Clin Pharmacol. 2002 Jun;16(3):161-73. doi: 10.1046/j.1472-8206.2002.00098.x. Fundam Clin Pharmacol. 2002. PMID: 12165064

9

The application of in vitro methods to safety pharmacology.

Wakefield ID, Pollard C, Redfern WS, Hammond TG, Valentin JP. Wakefield ID, et al. Among authors: hammond tg. Fundam Clin Pharmacol. 2002 Jun;16(3):209-18. doi: 10.1046/j.1472-8206.2002.00099.x. Fundam Clin Pharmacol. 2002. PMID: 12165068 Review.

10

Methods of collecting and evaluating non-clinical cardiac electrophysiology data in the pharmaceutical industry: results of an international survey.

Hammond TG, Carlsson L, Davis AS, Lynch WG, MacKenzie I, Redfern WS, Sullivan AT, Camm AJ. Hammond TG, et al. Cardiovasc Res. 2001 Mar;49(4):741-50. doi: 10.1016/s0008-6363(00)00310-2. Cardiovasc Res. 2001. PMID: 11230973

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