Brunzelle JS - Search Results

1

Structural and functional analysis of SET8, a histone H4 Lys-20 methyltransferase.

Couture JF, Collazo E, Brunzelle JS, Trievel RC. Couture JF, et al. Among authors: brunzelle js. Genes Dev. 2005 Jun 15;19(12):1455-65. doi: 10.1101/gad.1318405. Epub 2005 Jun 2. Genes Dev. 2005. PMID: 15933070 Free PMC article.

2

Specificity and mechanism of JMJD2A, a trimethyllysine-specific histone demethylase.

Couture JF, Collazo E, Ortiz-Tello PA, Brunzelle JS, Trievel RC. Couture JF, et al. Among authors: brunzelle js. Nat Struct Mol Biol. 2007 Aug;14(8):689-95. doi: 10.1038/nsmb1273. Epub 2007 Jun 24. Nat Struct Mol Biol. 2007. PMID: 17589523

3

Structural origins for the product specificity of SET domain protein methyltransferases.

Couture JF, Dirk LM, Brunzelle JS, Houtz RL, Trievel RC. Couture JF, et al. Among authors: brunzelle js. Proc Natl Acad Sci U S A. 2008 Dec 30;105(52):20659-64. doi: 10.1073/pnas.0806712105. Epub 2008 Dec 16. Proc Natl Acad Sci U S A. 2008. PMID: 19088188 Free PMC article.

4

SET7/9 catalytic mutants reveal the role of active site water molecules in lysine multiple methylation.

Del Rizzo PA, Couture JF, Dirk LM, Strunk BS, Roiko MS, Brunzelle JS, Houtz RL, Trievel RC. Del Rizzo PA, et al. Among authors: brunzelle js. J Biol Chem. 2010 Oct 8;285(41):31849-58. doi: 10.1074/jbc.M110.114587. Epub 2010 Aug 1. J Biol Chem. 2010. PMID: 20675860 Free PMC article.

5

Structural and biochemical insights into MLL1 core complex assembly.

Avdic V, Zhang P, Lanouette S, Groulx A, Tremblay V, Brunzelle J, Couture JF. Avdic V, et al. Structure. 2011 Jan 12;19(1):101-8. doi: 10.1016/j.str.2010.09.022. Structure. 2011. PMID: 21220120 Free article.

6

Crystal structure of the trithorax group protein ASH2L reveals a forkhead-like DNA binding domain.

Sarvan S, Avdic V, Tremblay V, Chaturvedi CP, Zhang P, Lanouette S, Blais A, Brunzelle JS, Brand M, Couture JF. Sarvan S, et al. Among authors: brunzelle js. Nat Struct Mol Biol. 2011 Jun 5;18(7):857-9. doi: 10.1038/nsmb.2093. Nat Struct Mol Biol. 2011. PMID: 21642971 Free PMC article.

7

Crystal structures of histone and p53 methyltransferase SmyD2 reveal a conformational flexibility of the autoinhibitory C-terminal domain.

Jiang Y, Sirinupong N, Brunzelle J, Yang Z. Jiang Y, et al. PLoS One. 2011;6(6):e21640. doi: 10.1371/journal.pone.0021640. Epub 2011 Jun 28. PLoS One. 2011. PMID: 21738746 Free PMC article.

8

The plasticity of WDR5 peptide-binding cleft enables the binding of the SET1 family of histone methyltransferases.

Zhang P, Lee H, Brunzelle JS, Couture JF. Zhang P, et al. Among authors: brunzelle js. Nucleic Acids Res. 2012 May;40(9):4237-46. doi: 10.1093/nar/gkr1235. Epub 2012 Jan 20. Nucleic Acids Res. 2012. PMID: 22266653 Free PMC article.

9

Structure and regulon of Campylobacter jejuni ferric uptake regulator Fur define apo-Fur regulation.

Butcher J, Sarvan S, Brunzelle JS, Couture JF, Stintzi A. Butcher J, et al. Among authors: brunzelle js. Proc Natl Acad Sci U S A. 2012 Jun 19;109(25):10047-52. doi: 10.1073/pnas.1118321109. Epub 2012 Jun 4. Proc Natl Acad Sci U S A. 2012. PMID: 22665794 Free PMC article.

10

Crystal structure of Saccharomyces cerevisiae Aro8, a putative α-aminoadipate aminotransferase.

Bulfer SL, Brunzelle JS, Trievel RC. Bulfer SL, et al. Among authors: brunzelle js. Protein Sci. 2013 Oct;22(10):1417-24. doi: 10.1002/pro.2315. Epub 2013 Aug 28. Protein Sci. 2013. PMID: 23893908 Free PMC article.

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