Lim SP - Search Results

1

Functional profiling of recombinant NS3 proteases from all four serotypes of dengue virus using tetrapeptide and octapeptide substrate libraries.

Li J, Lim SP, Beer D, Patel V, Wen D, Tumanut C, Tully DC, Williams JA, Jiricek J, Priestle JP, Harris JL, Vasudevan SG. Li J, et al. Among authors: lim sp. J Biol Chem. 2005 Aug 5;280(31):28766-74. doi: 10.1074/jbc.M500588200. Epub 2005 Jun 1. J Biol Chem. 2005. PMID: 15932883 Free article.

2

Peptide inhibitors of Dengue virus NS3 protease. Part 1: Warhead.

Yin Z, Patel SJ, Wang WL, Wang G, Chan WL, Rao KR, Alam J, Jeyaraj DA, Ngew X, Patel V, Beer D, Lim SP, Vasudevan SG, Keller TH. Yin Z, et al. Among authors: lim sp. Bioorg Med Chem Lett. 2006 Jan 1;16(1):36-9. doi: 10.1016/j.bmcl.2005.09.062. Epub 2005 Oct 21. Bioorg Med Chem Lett. 2006. PMID: 16246553

3

Peptide inhibitors of dengue virus NS3 protease. Part 2: SAR study of tetrapeptide aldehyde inhibitors.

Yin Z, Patel SJ, Wang WL, Chan WL, Ranga Rao KR, Wang G, Ngew X, Patel V, Beer D, Knox JE, Ma NL, Ehrhardt C, Lim SP, Vasudevan SG, Keller TH. Yin Z, et al. Among authors: lim sp. Bioorg Med Chem Lett. 2006 Jan 1;16(1):40-3. doi: 10.1016/j.bmcl.2005.09.049. Epub 2005 Oct 21. Bioorg Med Chem Lett. 2006. PMID: 16246563

4

Dengue protease activity: the structural integrity and interaction of NS2B with NS3 protease and its potential as a drug target.

Phong WY, Moreland NJ, Lim SP, Wen D, Paradkar PN, Vasudevan SG. Phong WY, et al. Among authors: lim sp. Biosci Rep. 2011 Oct;31(5):399-409. doi: 10.1042/BSR20100142. Biosci Rep. 2011. PMID: 21329491

5

Structural basis for the activation of flaviviral NS3 proteases from dengue and West Nile virus.

Erbel P, Schiering N, D'Arcy A, Renatus M, Kroemer M, Lim SP, Yin Z, Keller TH, Vasudevan SG, Hommel U. Erbel P, et al. Among authors: lim sp. Nat Struct Mol Biol. 2006 Apr;13(4):372-3. doi: 10.1038/nsmb1073. Epub 2006 Mar 12. Nat Struct Mol Biol. 2006. PMID: 16532006

6

Peptide inhibitors of West Nile NS3 protease: SAR study of tetrapeptide aldehyde inhibitors.

Knox JE, Ma NL, Yin Z, Patel SJ, Wang WL, Chan WL, Ranga Rao KR, Wang G, Ngew X, Patel V, Beer D, Lim SP, Vasudevan SG, Keller TH. Knox JE, et al. Among authors: lim sp. J Med Chem. 2006 Nov 2;49(22):6585-90. doi: 10.1021/jm0607606. J Med Chem. 2006. PMID: 17064076

7

Mutagenesis of the dengue virus type 2 NS5 methyltransferase domain.

Kroschewski H, Lim SP, Butcher RE, Yap TL, Lescar J, Wright PJ, Vasudevan SG, Davidson AD. Kroschewski H, et al. Among authors: lim sp. J Biol Chem. 2008 Jul 11;283(28):19410-21. doi: 10.1074/jbc.M800613200. Epub 2008 May 9. J Biol Chem. 2008. PMID: 18469001 Free article.

8

Yellow fever virus NS3 protease: peptide-inhibition studies.

Löhr K, Knox JE, Phong WY, Ma NL, Yin Z, Sampath A, Patel SJ, Wang WL, Chan WL, Rao KRR, Wang G, Vasudevan SG, Keller TH, Lim SP. Löhr K, et al. Among authors: lim sp. J Gen Virol. 2007 Aug;88(Pt 8):2223-2227. doi: 10.1099/vir.0.82735-0. J Gen Virol. 2007. PMID: 17622626

9

A scintillation proximity assay for dengue virus NS5 2'-O-methyltransferase-kinetic and inhibition analyses.

Lim SP, Wen D, Yap TL, Yan CK, Lescar J, Vasudevan SG. Lim SP, et al. Antiviral Res. 2008 Dec;80(3):360-9. doi: 10.1016/j.antiviral.2008.08.005. Epub 2008 Sep 20. Antiviral Res. 2008. PMID: 18809436

10

A fluorescence quenching assay to discriminate between specific and nonspecific inhibitors of dengue virus protease.

Bodenreider C, Beer D, Keller TH, Sonntag S, Wen D, Yap L, Yau YH, Shochat SG, Huang D, Zhou T, Caflisch A, Su XC, Ozawa K, Otting G, Vasudevan SG, Lescar J, Lim SP. Bodenreider C, et al. Among authors: lim sp. Anal Biochem. 2009 Dec 15;395(2):195-204. doi: 10.1016/j.ab.2009.08.013. Epub 2009 Aug 13. Anal Biochem. 2009. PMID: 19682971

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