Shimohata H - Search Results

1

MafA is a key regulator of glucose-stimulated insulin secretion.

Zhang C, Moriguchi T, Kajihara M, Esaki R, Harada A, Shimohata H, Oishi H, Hamada M, Morito N, Hasegawa K, Kudo T, Engel JD, Yamamoto M, Takahashi S. Zhang C, et al. Among authors: shimohata h. Mol Cell Biol. 2005 Jun;25(12):4969-76. doi: 10.1128/MCB.25.12.4969-4976.2005. Mol Cell Biol. 2005. PMID: 15923615 Free PMC article.

2

MafK overexpression in pancreatic beta-cells caused impairment of glucose-stimulated insulin secretion.

Shimohata H, Yoh K, Morito N, Shimano H, Kudo T, Takahashi S. Shimohata H, et al. Biochem Biophys Res Commun. 2006 Aug 4;346(3):671-80. doi: 10.1016/j.bbrc.2006.05.184. Epub 2006 Jun 8. Biochem Biophys Res Commun. 2006. PMID: 16780794

3

Transgenic overexpression of GATA-3 in T lymphocytes improves autoimmune glomerulonephritis in mice with a BXSB/MpJ-Yaa genetic background.

Yoh K, Shibuya K, Morito N, Nakano T, Ishizaki K, Shimohata H, Nose M, Izui S, Shibuya A, Koyama A, Engel JD, Yamamoto M, Takahashi S. Yoh K, et al. Among authors: shimohata h. J Am Soc Nephrol. 2003 Oct;14(10):2494-502. doi: 10.1097/01.asn.0000086473.23379.25. J Am Soc Nephrol. 2003. PMID: 14514727

4

MafA-deficient and beta cell-specific MafK-overexpressing hybrid transgenic mice develop human-like severe diabetic nephropathy.

Shimohata H, Yoh K, Fujita A, Morito N, Ojima M, Tanaka H, Hirayama K, Kobayashi M, Kudo T, Yamagata K, Takahashi S. Shimohata H, et al. Biochem Biophys Res Commun. 2009 Nov 13;389(2):235-40. doi: 10.1016/j.bbrc.2009.08.124. Epub 2009 Aug 26. Biochem Biophys Res Commun. 2009. PMID: 19715672

5

A novel diabetes mellitus mouse model, MAFA-deficient and beta cell-specific MAFK-overexpressing hybrid transgenic mice, developed severe diabetic nephropathy and improved with TCV-116 (candesartan cilexetil) treatment.

Fujita A, Yoh K, Shimohata H, Morito N, Ojima M, Okamura M, Takahashi S, Yamagata K. Fujita A, et al. Among authors: shimohata h. Exp Anim. 2012;61(1):49-57. doi: 10.1538/expanim.61.49. Exp Anim. 2012. PMID: 22293672 Free article.

6

Hyperglycemia induces oxidative and nitrosative stress and increases renal functional impairment in Nrf2-deficient mice.

Yoh K, Hirayama A, Ishizaki K, Yamada A, Takeuchi M, Yamagishi S, Morito N, Nakano T, Ojima M, Shimohata H, Itoh K, Takahashi S, Yamamoto M. Yoh K, et al. Among authors: shimohata h. Genes Cells. 2008 Nov;13(11):1159-70. doi: 10.1111/j.1365-2443.2008.01234.x. Genes Cells. 2008. PMID: 19090810 Free article.

7

Overexpression of Mafb in podocytes protects against diabetic nephropathy.

Morito N, Yoh K, Ojima M, Okamura M, Nakamura M, Hamada M, Shimohata H, Moriguchi T, Yamagata K, Takahashi S. Morito N, et al. Among authors: shimohata h. J Am Soc Nephrol. 2014 Nov;25(11):2546-57. doi: 10.1681/ASN.2013090993. Epub 2014 Apr 10. J Am Soc Nephrol. 2014. PMID: 24722438 Free PMC article.

8

Overexpression of c-Maf contributes to T-cell lymphoma in both mice and human.

Morito N, Yoh K, Fujioka Y, Nakano T, Shimohata H, Hashimoto Y, Yamada A, Maeda A, Matsuno F, Hata H, Suzuki A, Imagawa S, Mitsuya H, Esumi H, Koyama A, Yamamoto M, Mori N, Takahashi S. Morito N, et al. Among authors: shimohata h. Cancer Res. 2006 Jan 15;66(2):812-9. doi: 10.1158/0008-5472.CAN-05-2154. Cancer Res. 2006. PMID: 16424013

9

Overexpression of T-bet in T cells accelerates autoimmune glomerulonephritis in mice with a dominant Th1 background.

Shimohata H, Yamada A, Yoh K, Ishizaki K, Morito N, Yamagata K, Takahashi S. Shimohata H, et al. J Nephrol. 2009 Jan-Feb;22(1):123-9. J Nephrol. 2009. PMID: 19229827

10

Th1 and type 1 cytotoxic T cells dominate responses in T-bet overexpression transgenic mice that develop contact dermatitis.

Ishizaki K, Yamada A, Yoh K, Nakano T, Shimohata H, Maeda A, Fujioka Y, Morito N, Kawachi Y, Shibuya K, Otsuka F, Shibuya A, Takahashi S. Ishizaki K, et al. Among authors: shimohata h. J Immunol. 2007 Jan 1;178(1):605-12. doi: 10.4049/jimmunol.178.1.605. J Immunol. 2007. PMID: 17182601

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