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Inhibition of gamma-secretase activity reduces Abeta production, reduces oxidative stress, increases mitochondrial activity and leads to reduced vulnerability to apoptosis: Implications for the treatment of Alzheimer's disease.
Sheng B, Gong K, Niu Y, Liu L, Yan Y, Lu G, Zhang L, Hu M, Zhao N, Zhang X, Tang P, Gong Y. Sheng B, et al. Among authors: gong y, gong k. Free Radic Biol Med. 2009 May 15;46(10):1362-75. doi: 10.1016/j.freeradbiomed.2009.02.018. Epub 2009 Mar 3. Free Radic Biol Med. 2009. PMID: 19264123
LEF-1 activates the transcription of E2F1.
Zhou F, Zhang L, Gong K, Lu G, Sheng B, Wang A, Zhao N, Zhang X, Gong Y. Zhou F, et al. Among authors: gong y, gong k. Biochem Biophys Res Commun. 2008 Jan 4;365(1):149-53. doi: 10.1016/j.bbrc.2007.10.138. Epub 2007 Oct 31. Biochem Biophys Res Commun. 2008. PMID: 17980157
1,024 results