Farr CL - Search Results

1

Functional defects due to spacer-region mutations of human mitochondrial DNA polymerase in a family with an ataxia-myopathy syndrome.

Luoma PT, Luo N, Löscher WN, Farr CL, Horvath R, Wanschitz J, Kiechl S, Kaguni LS, Suomalainen A. Luoma PT, et al. Among authors: farr cl. Hum Mol Genet. 2005 Jul 15;14(14):1907-20. doi: 10.1093/hmg/ddi196. Epub 2005 May 25. Hum Mol Genet. 2005. PMID: 15917273

2

Functional analysis of H. sapiens DNA polymerase gamma spacer mutation W748S with and without common variant E1143G.

Palin EJ, Lesonen A, Farr CL, Euro L, Suomalainen A, Kaguni LS. Palin EJ, et al. Among authors: farr cl. Biochim Biophys Acta. 2010 Jun;1802(6):545-51. doi: 10.1016/j.bbadis.2010.02.003. Epub 2010 Feb 12. Biochim Biophys Acta. 2010. PMID: 20153822 Free PMC article.

3

The accessory subunit of DNA polymerase gamma is essential for mitochondrial DNA maintenance and development in Drosophila melanogaster.

Iyengar B, Luo N, Farr CL, Kaguni LS, Campos AR. Iyengar B, et al. Among authors: farr cl. Proc Natl Acad Sci U S A. 2002 Apr 2;99(7):4483-8. doi: 10.1073/pnas.072664899. Epub 2002 Mar 26. Proc Natl Acad Sci U S A. 2002. PMID: 11917141 Free PMC article.

4

Physiological and biochemical defects in functional interactions of mitochondrial DNA polymerase and DNA-binding mutants of single-stranded DNA-binding protein.

Farr CL, Matsushima Y, Lagina AT 3rd, Luo N, Kaguni LS. Farr CL, et al. J Biol Chem. 2004 Apr 23;279(17):17047-53. doi: 10.1074/jbc.M400283200. Epub 2004 Jan 30. J Biol Chem. 2004. PMID: 14754882 Free article.

5

A novel processive mechanism for DNA synthesis revealed by structure, modeling and mutagenesis of the accessory subunit of human mitochondrial DNA polymerase.

Fan L, Kim S, Farr CL, Schaefer KT, Randolph KM, Tainer JA, Kaguni LS. Fan L, et al. Among authors: farr cl. J Mol Biol. 2006 May 19;358(5):1229-43. doi: 10.1016/j.jmb.2006.02.073. Epub 2006 Mar 15. J Mol Biol. 2006. PMID: 16574152 Free PMC article.

6

Modular architecture of the hexameric human mitochondrial DNA helicase.

Ziebarth TD, Farr CL, Kaguni LS. Ziebarth TD, et al. Among authors: farr cl. J Mol Biol. 2007 Apr 13;367(5):1382-91. doi: 10.1016/j.jmb.2007.01.079. Epub 2007 Feb 7. J Mol Biol. 2007. PMID: 17324440 Free PMC article.

7

Accessory subunit of mitochondrial DNA polymerase from Drosophila embryos. Cloning, molecular analysis, and association in the native enzyme.

Wang Y, Farr CL, Kaguni LS. Wang Y, et al. Among authors: farr cl. J Biol Chem. 1997 May 23;272(21):13640-6. doi: 10.1074/jbc.272.21.13640. J Biol Chem. 1997. PMID: 9153213 Free article.

8

Functional interactions of mitochondrial DNA polymerase and single-stranded DNA-binding protein. Template-primer DNA binding and initiation and elongation of DNA strand synthesis.

Farr CL, Wang Y, Kaguni LS. Farr CL, et al. J Biol Chem. 1999 May 21;274(21):14779-85. doi: 10.1074/jbc.274.21.14779. J Biol Chem. 1999. PMID: 10329675 Free article.

9

Purification strategies for Drosophila mtDNA replication proteins in native and recombinant form. DNA polymerase gamma.

Farr CL, Kaguni LS. Farr CL, et al. Methods Mol Biol. 2002;197:273-83. doi: 10.1385/1-59259-284-8:273. Methods Mol Biol. 2002. PMID: 12013802 No abstract available.

10

Purification strategies for Drosophila mtDNA replication proteins in native and recombinant form. Mitochondrial single-stranded DNA-binding protein.

Farr CL, Kaguni LS. Farr CL, et al. Methods Mol Biol. 2002;197:285-94. doi: 10.1385/1-59259-284-8:285. Methods Mol Biol. 2002. PMID: 12013803 No abstract available.

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