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Cathepsin S inhibitors as novel immunomodulators.
Thurmond RL, Sun S, Karlsson L, Edwards JP. Thurmond RL, et al. Among authors: sun s. Curr Opin Investig Drugs. 2005 May;6(5):473-82. Curr Opin Investig Drugs. 2005. PMID: 15912960 Review.
Identification of a potent and selective noncovalent cathepsin S inhibitor.
Thurmond RL, Sun S, Sehon CA, Baker SM, Cai H, Gu Y, Jiang W, Riley JP, Williams KN, Edwards JP, Karlsson L. Thurmond RL, et al. Among authors: sun s. J Pharmacol Exp Ther. 2004 Jan;308(1):268-76. doi: 10.1124/jpet.103.056879. Epub 2003 Oct 17. J Pharmacol Exp Ther. 2004. PMID: 14566006
The SAR of 4-substituted (6,6-bicyclic) piperidine cathepsin S inhibitors.
Grice CA, Tays K, Khatuya H, Gustin DJ, Butler CR, Wei J, Sehon CA, Sun S, Gu Y, Jiang W, Thurmond RL, Karlsson L, Edwards JP. Grice CA, et al. Among authors: sun s. Bioorg Med Chem Lett. 2006 Apr 15;16(8):2209-12. doi: 10.1016/j.bmcl.2006.01.038. Epub 2006 Feb 3. Bioorg Med Chem Lett. 2006. PMID: 16458510
Pyrazole-based cathepsin S inhibitors with improved cellular potency.
Wei J, Pio BA, Cai H, Meduna SP, Sun S, Gu Y, Jiang W, Thurmond RL, Karlsson L, Edwards JP. Wei J, et al. Among authors: sun s. Bioorg Med Chem Lett. 2007 Oct 15;17(20):5525-8. doi: 10.1016/j.bmcl.2007.08.038. Epub 2007 Aug 22. Bioorg Med Chem Lett. 2007. PMID: 17822900
Pyrazole-based cathepsin S inhibitors with arylalkynes as P1 binding elements.
Ameriks MK, Axe FU, Bembenek SD, Edwards JP, Gu Y, Karlsson L, Randal M, Sun S, Thurmond RL, Zhu J. Ameriks MK, et al. Among authors: sun s. Bioorg Med Chem Lett. 2009 Nov 1;19(21):6131-4. doi: 10.1016/j.bmcl.2009.09.014. Epub 2009 Sep 10. Bioorg Med Chem Lett. 2009. PMID: 19773165
20,792 results
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