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Targeting CLDN6 in germ cell tumors by an antibody-drug-conjugate and studying therapy resistance of yolk-sac tumors to identify and screen specific therapeutic options.
Skowron MA, Kotthoff M, Bremmer F, Ruhnke K, Parmaksiz F, Richter A, Küffer S, Reuter-Jessen K, Pauls S, Stefanski A, Ströbel P, Stühler K, Nettersheim D. Skowron MA, et al. Among authors: stuhler k. Mol Med. 2023 Mar 29;29(1):40. doi: 10.1186/s10020-023-00636-3. Mol Med. 2023. PMID: 36991316 Free PMC article.
Tacedinaline (CI-994), a class I HDAC inhibitor, targets intrinsic tumor growth and leptomeningeal dissemination in MYC-driven medulloblastoma while making them susceptible to anti-CD47-induced macrophage phagocytosis via NF-kB-TGM2 driven tumor inflammation.
Marquardt V, Theruvath J, Pauck D, Picard D, Qin N, Blümel L, Maue M, Bartl J, Ahmadov U, Langini M, Meyer FD, Cole A, Cruz-Cruz J, Graef CM, Wölfl M, Milde T, Witt O, Erdreich-Epstein A, Leprivier G, Kahlert U, Stefanski A, Stühler K, Keir ST, Bigner DD, Hauer J, Beez T, Knobbe-Thomsen CB, Fischer U, Felsberg J, Hansen FK, Vibhakar R, Venkatraman S, Cheshier SH, Reifenberger G, Borkhardt A, Kurz T, Remke M, Mitra S. Marquardt V, et al. Among authors: stuhler k. J Immunother Cancer. 2023 Jan;11(1):e005871. doi: 10.1136/jitc-2022-005871. J Immunother Cancer. 2023. PMID: 36639156 Free PMC article.
Cardiac injection of USSC boosts remuscularization of the infarcted heart by shaping the T-cell response.
Ding Z, Tan K, Alter C, Temme S, Bouvain P, Owenier C, Hänsch S, Wesselborg S, Peter C, Weidtkamp-Peters S, Flögel U, Schira-Heinen J, Stühler K, Hesse J, Kögler G, Schrader J. Ding Z, et al. Among authors: stuhler k. J Mol Cell Cardiol. 2023 Feb;175:29-43. doi: 10.1016/j.yjmcc.2022.11.006. Epub 2022 Dec 6. J Mol Cell Cardiol. 2023. PMID: 36493853 Free article.
The mycotoxin viriditoxin induces leukemia- and lymphoma-specific apoptosis by targeting mitochondrial metabolism.
Stuhldreier F, Schmitt L, Lenz T, Hinxlage I, Zimmermann M, Wollnitzke P, Schliehe-Diecks J, Liu Y, Jäger P, Geyh S, Teusch N, Peter C, Bhatia S, Haas R, Levkau B, Reichert AS, Stühler K, Proksch P, Stork B, Wesselborg S. Stuhldreier F, et al. Among authors: stuhler k. Cell Death Dis. 2022 Nov 8;13(11):938. doi: 10.1038/s41419-022-05356-w. Cell Death Dis. 2022. PMID: 36347842 Free PMC article.
A neo-functionalized homolog of host transmembrane protein controls localization of bacterial endosymbionts in the trypanosomatid Novymonas esmeraldas.
Zakharova A, Tashyreva D, Butenko A, Morales J, Saura A, Svobodová M, Poschmann G, Nandipati S, Zakharova A, Noyvert D, Gahura O, Týč J, Stühler K, Kostygov AY, Nowack ECM, Lukeš J, Yurchenko V. Zakharova A, et al. Among authors: stuhler k. Curr Biol. 2023 Jul 10;33(13):2690-2701.e5. doi: 10.1016/j.cub.2023.04.060. Epub 2023 May 17. Curr Biol. 2023. PMID: 37201521 Free article.
Proteomics: techniques and applications in cancer research.
Schramm A, Apostolov O, Sitek B, Pfeiffer K, Stühler K, Meyer HE, Havers W, Eggert A. Schramm A, et al. Among authors: stuhler k. Klin Padiatr. 2003 Nov-Dec;215(6):293-7. doi: 10.1055/s-2003-45502. Klin Padiatr. 2003. PMID: 14677091
176 results