Optimization of ligand and lipophilic efficiency to identify an in vivo active furano-pyrimidine Aurora kinase inhibitor.
Shiao HY, Coumar MS, Chang CW, Ke YY, Chi YH, Chu CY, Sun HY, Chen CH, Lin WH, Fung KS, Kuo PC, Huang CT, Chang KY, Lu CT, Hsu JT, Chen CT, Jiaang WT, Chao YS, Hsieh HP.
Shiao HY, et al. Among authors: chang cw, chang ky.
J Med Chem. 2013 Jul 11;56(13):5247-60. doi: 10.1021/jm4006059. Epub 2013 Jun 28.
J Med Chem. 2013.
PMID: 23808327