Chacko AD - Search Results

1

SEPT9_v4 expression induces morphological change, increased motility and disturbed polarity.

Chacko AD, Hyland PL, McDade SS, Hamilton PW, Russell SH, Hall PA. Chacko AD, et al. J Pathol. 2005 Aug;206(4):458-65. doi: 10.1002/path.1794. J Pathol. 2005. PMID: 15902694

2

Expression of the SEPT9_i4 isoform confers resistance to microtubule-interacting drugs.

Chacko AD, McDade SS, Chanduloy S, Church SW, Kennedy R, Price J, Hall PA, Russell SE. Chacko AD, et al. Cell Oncol (Dordr). 2012 Apr;35(2):85-93. doi: 10.1007/s13402-011-0066-0. Epub 2012 Jan 26. Cell Oncol (Dordr). 2012. PMID: 22278362

3

Acquired differential regulation of caspase-8 in cisplatin-resistant non-small-cell lung cancer.

Paul I, Chacko AD, Stasik I, Busacca S, Crawford N, McCoy F, McTavish N, Wilson B, Barr M, O'Byrne KJ, Longley DB, Fennell DA. Paul I, et al. Among authors: chacko ad. Cell Death Dis. 2012 Dec 20;3(12):e449. doi: 10.1038/cddis.2012.186. Cell Death Dis. 2012. PMID: 23254292 Free PMC article.

4

Platinum resistant cancer cells conserve sensitivity to BH3 domains and obatoclax induced mitochondrial apoptosis.

Crawford N, Chacko AD, Savage KI, McCoy F, Redmond K, Longley DB, Fennell DA. Crawford N, et al. Among authors: chacko ad. Apoptosis. 2011 Mar;16(3):311-20. doi: 10.1007/s10495-010-0561-1. Apoptosis. 2011. PMID: 21107700

5

Voltage dependent anion channel-1 regulates death receptor mediated apoptosis by enabling cleavage of caspase-8.

Chacko AD, Liberante F, Paul I, Longley DB, Fennell DA. Chacko AD, et al. BMC Cancer. 2010 Jul 20;10:380. doi: 10.1186/1471-2407-10-380. BMC Cancer. 2010. PMID: 20646307 Free PMC article.

6

Machine vision based stochastic analysis of cancer cell mitochondrial dysfunction induced by a BH3 domain.

Chacko AD, Crawford NT, Johnston PG, Fennell DA. Chacko AD, et al. Apoptosis. 2008 Nov;13(11):1386-93. doi: 10.1007/s10495-008-0262-1. Apoptosis. 2008. PMID: 18814032

7

Exploiting BH3 only protein function for effective cancer therapy.

Fennell DA, Chacko A. Fennell DA, et al. Front Biosci. 2008 May 1;13:6682-92. doi: 10.2741/3181. Front Biosci. 2008. PMID: 18508687 Review.

8

The Bcl-2 repertoire of mesothelioma spheroids underlies acquired apoptotic multicellular resistance.

Barbone D, Ryan JA, Kolhatkar N, Chacko AD, Jablons DM, Sugarbaker DJ, Bueno R, Letai AG, Coussens LM, Fennell DA, Broaddus VC. Barbone D, et al. Among authors: chacko ad. Cell Death Dis. 2011 Jun 23;2(6):e174. doi: 10.1038/cddis.2011.58. Cell Death Dis. 2011. PMID: 21697949 Free PMC article.

9

BAK and NOXA are critical determinants of mitochondrial apoptosis induced by bortezomib in mesothelioma.

Busacca S, Chacko AD, Klabatsa A, Arthur K, Sheaff M, Barbone D, Mutti L, Gunasekharan VK, Gorski JJ, El-Tanani M, Broaddus VC, Gaudino G, Fennell DA. Busacca S, et al. Among authors: chacko ad. PLoS One. 2013 Jun 7;8(6):e65489. doi: 10.1371/journal.pone.0065489. Print 2013. PLoS One. 2013. PMID: 23762382 Free PMC article.

10

Dynamical systems analysis of mitochondrial BAK activation kinetics predicts resistance to BH3 domains.

Grills C, Crawford N, Chacko A, Johnston PG, O'Rourke F, Fennell DA. Grills C, et al. PLoS One. 2008 Aug 22;3(8):e3038. doi: 10.1371/journal.pone.0003038. PLoS One. 2008. PMID: 18725943 Free PMC article.

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