Gudmundsson OS - Search Results

1

Delineation of human peptide transporter 1 (hPepT1)-mediated uptake and transport of substrates with varying transporter affinities utilizing stably transfected hPepT1/Madin-Darby canine kidney clones and Caco-2 cells.

Bhardwaj RK, Herrera-Ruiz D, Sinko PJ, Gudmundsson OS, Knipp G. Bhardwaj RK, et al. Among authors: gudmundsson os. J Pharmacol Exp Ther. 2005 Sep;314(3):1093-100. doi: 10.1124/jpet.105.087148. Epub 2005 May 18. J Pharmacol Exp Ther. 2005. PMID: 15901802

2

A novel hPepT1 stably transfected cell line: establishing a correlation between expression and function.

Herrera-Ruiz D, Faria TN, Bhardwaj RK, Timoszyk J, Gudmundsson OS, Moench P, Wall DA, Smith RL, Knipp GT. Herrera-Ruiz D, et al. Among authors: gudmundsson os. Mol Pharm. 2004 Mar-Apr;1(2):136-44. doi: 10.1021/mp034011l. Mol Pharm. 2004. PMID: 15832510

3

Spatial expression patterns of peptide transporters in the human and rat gastrointestinal tracts, Caco-2 in vitro cell culture model, and multiple human tissues.

Herrera-Ruiz D, Wang Q, Gudmundsson OS, Cook TJ, Smith RL, Faria TN, Knipp GT. Herrera-Ruiz D, et al. Among authors: gudmundsson os. AAPS PharmSci. 2001;3(1):E9. doi: 10.1208/ps030109. AAPS PharmSci. 2001. PMID: 11741260 Free PMC article.

4

Expression of multiple drug resistance conferring proteins in normal Chinese and Caucasian small and large intestinal tissue samples.

Wang Q, Bhardwaj RK, Herrera-Ruiz D, Hanna NN, Hanna IT, Gudmundsson OS, Buranachokpaisan T, Hidalgo IJ, Knipp GT. Wang Q, et al. Among authors: gudmundsson os. Mol Pharm. 2004 Nov-Dec;1(6):447-54. doi: 10.1021/mp049942r. Mol Pharm. 2004. PMID: 16028356

5

Acyloxyalkoxy-based cyclic prodrugs of opioid peptides: evaluation of the chemical and enzymatic stability as well as their transport properties across Caco-2 cell monolayers.

Bak A, Gudmundsson OS, Friis GJ, Siahaan TJ, Borchardt RT. Bak A, et al. Among authors: gudmundsson os. Pharm Res. 1999 Jan;16(1):24-9. doi: 10.1023/a:1018854308829. Pharm Res. 1999. PMID: 9950274

6

A computational model for the prediction of aqueous solubility that includes crystal packing, intrinsic solubility, and ionization effects.

Johnson SR, Chen XQ, Murphy D, Gudmundsson O. Johnson SR, et al. Mol Pharm. 2007 Jul-Aug;4(4):513-23. doi: 10.1021/mp070030+. Epub 2007 Jun 1. Mol Pharm. 2007. PMID: 17539661

7

Synthesis and evaluation of the physicochemical properties of esterase-sensitive cyclic prodrugs of opioid peptides using coumarinic acid and phenylpropionic acid linkers.

Wang B, Nimkar K, Wang W, Zhang H, Shan D, Gudmundsson O, Gangwar S, Siahaan T, Borchardt RT. Wang B, et al. J Pept Res. 1999 Apr;53(4):370-82. doi: 10.1034/j.1399-3011.1999.00071.x. J Pept Res. 1999. PMID: 10406215

8

Coumarinic acid-based cyclic prodrugs of opioid peptides that exhibit metabolic stability to peptidases and excellent cellular permeability.

Gudmundsson OS, Pauletti GM, Wang W, Shan D, Zhang H, Wang B, Borchardt RT. Gudmundsson OS, et al. Pharm Res. 1999 Jan;16(1):7-15. doi: 10.1023/a:1018828207920. Pharm Res. 1999. PMID: 9950272

9

Phenylpropionic acid-based cyclic prodrugs of opioid peptides that exhibit metabolic stability to peptidases and excellent cellular permeation.

Gudmundsson OS, Nimkar K, Gangwar S, Siahaan T, Borchardt RT. Gudmundsson OS, et al. Pharm Res. 1999 Jan;16(1):16-23. doi: 10.1023/a:1018802324759. Pharm Res. 1999. PMID: 9950273

10

The effect of conformation on the membrane permeation of coumarinic acid- and phenylpropionic acid-based cyclic prodrugs of opioid peptides.

Gudmundsson OS, Jois SD, Vander Velde DG, Siahaan TJ, Wang B, Borchardt RT. Gudmundsson OS, et al. J Pept Res. 1999 Apr;53(4):383-92. doi: 10.1034/j.1399-3011.1999.00076.x. J Pept Res. 1999. PMID: 10406216

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