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Stable X chromosome inactivation involves the PRC1 Polycomb complex and requires histone MACROH2A1 and the CULLIN3/SPOP ubiquitin E3 ligase.
Hernández-Muñoz I, Lund AH, van der Stoop P, Boutsma E, Muijrers I, Verhoeven E, Nusinow DA, Panning B, Marahrens Y, van Lohuizen M. Hernández-Muñoz I, et al. Among authors: marahrens y. Proc Natl Acad Sci U S A. 2005 May 24;102(21):7635-40. doi: 10.1073/pnas.0408918102. Epub 2005 May 16. Proc Natl Acad Sci U S A. 2005. PMID: 15897469 Free PMC article.
Mammalian X chromosome inactivation.
Jaenisch R, Beard C, Lee J, Marahrens Y, Panning B. Jaenisch R, et al. Among authors: marahrens y. Novartis Found Symp. 1998;214:200-9; discussion 209-13, 228-32. doi: 10.1002/9780470515501.ch12. Novartis Found Symp. 1998. PMID: 9601019 Review.
BRCA1 supports XIST RNA concentration on the inactive X chromosome.
Ganesan S, Silver DP, Greenberg RA, Avni D, Drapkin R, Miron A, Mok SC, Randrianarison V, Brodie S, Salstrom J, Rasmussen TP, Klimke A, Marrese C, Marahrens Y, Deng CX, Feunteun J, Livingston DM. Ganesan S, et al. Among authors: marahrens y. Cell. 2002 Nov 1;111(3):393-405. doi: 10.1016/s0092-8674(02)01052-8. Cell. 2002. PMID: 12419249 Free article.
A deletion at the mouse Xist gene exposes trans-effects that alter the heterochromatin of the inactive X chromosome and the replication time and DNA stability of both X chromosomes.
Diaz-Perez SV, Ferguson DO, Wang C, Csankovszki G, Wang C, Tsai SC, Dutta D, Perez V, Kim S, Eller CD, Salstrom J, Ouyang Y, Teitell MA, Kaltenboeck B, Chess A, Huang S, Marahrens Y. Diaz-Perez SV, et al. Among authors: marahrens y. Genetics. 2006 Nov;174(3):1115-33. doi: 10.1534/genetics.105.051375. Epub 2006 Sep 15. Genetics. 2006. PMID: 16980402 Free PMC article.
Role of the Xist gene in X chromosome choosing.
Marahrens Y, Loring J, Jaenisch R. Marahrens Y, et al. Cell. 1998 Mar 6;92(5):657-64. doi: 10.1016/s0092-8674(00)81133-2. Cell. 1998. PMID: 9506520 Free article.
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